REFORMATSKY REACTION OF ETHYL 4-CHLORO-4,4-DIFLUOROCROTONATE - PREPARATION OF ALPHA-SUBSTITUTED 4,4-DIFLUORO-3-BUTENOATES

被引:0
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作者
TSUKAMOTO, T [1 ]
KITAZUME, T [1 ]
机构
[1] TOKYO INST TECHNOL,DEPT BIOENGN,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reformatsky reagent derived from ethyl 4-chloro-4,4-difluorocrotonate was found to react with carbonyl compounds in the a-mode by using Zn-Cu couple to afford alpha-substituted 4,4-difluoro-3-butenoates.
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页码:977 / 979
页数:3
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