PRINCIPLES AND APPLICATIONS OF ION-EXCLUSION CHROMATOGRAPHY

Ion-exclusion chromatography is a relatively old technique that has been attracting increased attention. It is particularly useful for separating hydrophilic molecular species from one another and from large amounts of ionic materials. The basic principles and methodology of ion-exclusion chromatography are presented and illustrated with typical examples. Several recent developments in ion-exclusion chromatography are discussed. These include methods for the enhancement of conductivity detection of weakly ionized substances and a new method for the chromatographic separation and detection of water.