A NOVEL POLYLOCUS METHOD FOR LINKAGE ANALYSIS USING THE LOD-SCORE OR AFFECTED SIB-PAIR METHOD

被引：34
|
作者：
TERWILLIGER, JD
OTT, J
机构：
[1] Department of Genetics and Development, Columbia University, New York
来源：
GENETIC EPIDEMIOLOGY | 1993年 / 10卷 / 06期
关键词：
POLYLOCUS LINKAGE ANALYSIS; AFFECTED SIB-PAIR ANALYSIS; MARKER;
D O I：
10.1002/gepi.1370100625
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
A novel approach to combining data from multiple linked loci is proposed that can provide substantial increases in power over normal two-point linkage analysis or sib-pair analysis, with a substantial saving in computing time over traditional multipoint methods. (C) 1993 Wiley-Liss, Inc.
引用
收藏
页码：477 / 482
页数：6
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