SIB-PAIR LINKAGE ANALYSES OF ALZHEIMERS-DISEASE

被引：3
|
作者：
BAILEYWILSON, JE
BAMBA, V
机构：
[1] Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, Louisiana
来源：
GENETIC EPIDEMIOLOGY | 1993年 / 10卷 / 06期
关键词：
GENETIC ANALYSIS; NEURODEGENERATIVE DISORDER; ALZHEIMERS DISEASE;
D O I：
10.1002/gepi.1370100607
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Sib-pair linkage analyses were used to search for linkage to a set of chromosome 19 and 21 marker loci in two sets of families with Alzheimer's disease. The advantage of this technique is that no assumption is made about the mode of inheritance of the disease. Some mild suggestions of linkage were found in early-onset families for a chromosome 21 marker and in a set of late-onset families for a chromosome 19 marker. (C) 1993 Wiley-Liss, Inc.
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页码：371 / 376
页数：6
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