SIB-PAIR LINKAGE ANALYSES OF ALZHEIMERS-DISEASE

被引:3
|
作者
BAILEYWILSON, JE
BAMBA, V
机构
[1] Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans, Louisiana
关键词
GENETIC ANALYSIS; NEURODEGENERATIVE DISORDER; ALZHEIMERS DISEASE;
D O I
10.1002/gepi.1370100607
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Sib-pair linkage analyses were used to search for linkage to a set of chromosome 19 and 21 marker loci in two sets of families with Alzheimer's disease. The advantage of this technique is that no assumption is made about the mode of inheritance of the disease. Some mild suggestions of linkage were found in early-onset families for a chromosome 21 marker and in a set of late-onset families for a chromosome 19 marker. (C) 1993 Wiley-Liss, Inc.
引用
收藏
页码:371 / 376
页数:6
相关论文
共 50 条
  • [21] The phenotypic difference discards sib-pair QTL linkage information
    Wright, FA
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1997, 60 (03) : 740 - 742
  • [22] A multivariate approach for detecting linkage with sib-pair observations.
    Xu, X
    Tian, L
    Xu, X
    Wei, LJ
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 530 - 530
  • [23] A sib-pair regression model of linkage disequilibrium for quantitative traits
    Cardon, LR
    [J]. HUMAN HEREDITY, 2000, 50 (06) : 350 - 358
  • [24] Environmental covariates: Effects on the power of sib-pair linkage methods
    Mandal, DM
    Sorant, AJM
    Pugh, EW
    Marcus, SE
    Klein, AP
    Mathias, RA
    O'Neill, J
    Temiyakarn, LF
    Wilson, AF
    Bailey-Wilson, JE
    [J]. GENETIC EPIDEMIOLOGY, 1999, 17 : S643 - S648
  • [25] Gamma Mixed Model to Improve Sib-Pair Linkage Analysis
    Kim, Jeonghwan
    Suh, Young Ju
    Won, Sungho
    Nah, Jeung Weon
    Lee, Woojoo
    [J]. KOREAN JOURNAL OF APPLIED STATISTICS, 2015, 28 (02) : 221 - 230
  • [26] A SIMPLE CORRECTION FOR SIB-PAIR ANALYSES PERFORMED IN LARGE SIBSHIPS
    HODGE, SE
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1983, 35 (06) : A199 - A199
  • [27] SIB-PAIR LINKAGE ANALYSIS APPLIED TO PEDIGREES WITH MELANOMA AND DYSPLASTIC NEVI
    BAILEYWILSON, JE
    DOBBINS, TE
    [J]. CYTOGENETICS AND CELL GENETICS, 1992, 59 (2-3): : 176 - 178
  • [28] Haseman and Elston Sib-Pair Linkage Analysis: A Brief Historical Note
    DeFries, John C.
    [J]. BEHAVIOR GENETICS, 2010, 40 (01) : 1 - 2
  • [29] LINKAGE ANALYSIS IN ALZHEIMERS-DISEASE
    VAN BROECKHOVEN, C
    BACKHOVENS, H
    RAEYMAEKERS, P
    STINISSEN, P
    VANCAMP, G
    VANHUL, W
    WEHNERT, A
    DEWINTER, G
    GHEUENS, J
    VANDENBERGHE, A
    [J]. JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY, 1988, 26 (05): : 329 - 329
  • [30] Design considerations in a sib-pair study of linkage for susceptibility loci in cancer
    Kerber, Richard A.
    Amos, Christopher I.
    Yeap, Beow Y.
    Finkelstein, Dianne M.
    Thomas, Duncan C.
    [J]. BMC MEDICAL GENETICS, 2008, 9