SERPINB2—its regulation and interplay with aryl hydrocarbon receptor

被引：0
|
作者：
Damian Brauze
机构：
[1] Polish Academy of Sciences,Institute of Human Genetics
来源：
Journal of Applied Genetics | 2021年 / 62卷
关键词：
SERPINB2; Aryl hydrocarbon receptor; Immune response; Cancer development;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Despite many years of intensive investigation, real biological role of SERPINB2 is largely unknown. However, recent high throughput studies suggest its function in inflammation, influence on autoimmune disorders, and modulation of processes leading to carcinogenesis. SERPINB2 expression is acutely upregulated by many different stimuli, among others by aryl hydrocarbon receptor ligands. Mechanisms of regulation of SERPINB2 expression, involvement of the gene in processes leading to inflammation or carcinogenesis, and its interplay with aryl hydrocarbon receptor are subject of present review.
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页码：99 / 105
页数：6
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