SERPINB2—its regulation and interplay with aryl hydrocarbon receptor

被引：0
|
作者：
Damian Brauze
机构：
[1] Polish Academy of Sciences,Institute of Human Genetics
来源：
Journal of Applied Genetics | 2021年 / 62卷
关键词：
SERPINB2; Aryl hydrocarbon receptor; Immune response; Cancer development;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Despite many years of intensive investigation, real biological role of SERPINB2 is largely unknown. However, recent high throughput studies suggest its function in inflammation, influence on autoimmune disorders, and modulation of processes leading to carcinogenesis. SERPINB2 expression is acutely upregulated by many different stimuli, among others by aryl hydrocarbon receptor ligands. Mechanisms of regulation of SERPINB2 expression, involvement of the gene in processes leading to inflammation or carcinogenesis, and its interplay with aryl hydrocarbon receptor are subject of present review.
引用
收藏
页码：99 / 105
页数：6
相关论文
共 50 条
  • [21] Interplay between aryl hydrocarbon receptor signaling and inflammatory responses in melanoma
    Mengoni, M.
    Braun, A.
    Shridhar, N.
    Gaffal, E.
    Tueting, T.
    EXPERIMENTAL DERMATOLOGY, 2017, 26 (03) : E96 - E97
  • [22] Revisiting the biological roles of PAI2 (SERPINB2) in cancer
    David R. Croucher
    Darren N. Saunders
    Sergei Lobov
    Marie Ranson
    Nature Reviews Cancer, 2008, 8 : 535 - 545
  • [23] SerpinB2 is involved in cellular response upon UV irradiation
    Hajnalka Majoros
    Zsuzsanna Ujfaludi
    Barbara Nikolett Borsos
    Viktória Vivien Hudacsek
    Zita Nagy
    Frederic Coin
    Krisztina Buzas
    Ilona Kovács
    Tamás Bíró
    Imre Miklós Boros
    Tibor Pankotai
    Scientific Reports, 9
  • [24] SerpinB2 Regulates Immune Response in Kidney Injury and Aging
    Sen, Payel
    Helmke, Alexandra
    Liao, Chieh Ming
    Soerensen-Zender, Inga
    Rong, Song
    Braesen, Jan-Hinrich
    Melk, Anette
    Haller, Hermann
    von Vietinghoff, Sibylle
    Schmitt, Roland
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2020, 31 (05): : 983 - 995
  • [25] Regulation of subcellular localization of the aryl hydrocarbon receptor (Ahr)
    Richter, CA
    Tillitt, DE
    Hannink, M
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2001, 389 (02) : 207 - 217
  • [26] Role of the aryl hydrocarbon receptor in cell cycle regulation
    Puga, A
    Marlowe, J
    Barnes, S
    Chang, CY
    Maier, A
    Tan, ZQ
    Kerzee, JK
    Chang, XQ
    Strobeck, M
    Knudsen, ES
    TOXICOLOGY, 2002, 181 : 171 - 177
  • [27] Role of the aryl hydrocarbon receptor in cell cycle regulation
    Puga, A
    TOXICOLOGY, 2001, 164 (1-3) : 13 - 13
  • [28] Aryl hydrocarbon receptor (AhR) regulation of inflammation and cancer
    Platten, Michael
    TOXICOLOGY LETTERS, 2013, 221 : S29 - S29
  • [29] Regulation of gene expression and oncogenesis by the aryl hydrocarbon receptor
    Lorenz, Poellinger
    ACTA PHARMACOLOGICA SINICA, 2006, 27 : 36 - 36
  • [30] Differential Regulation of the Asthmatic Phenotype by the Aryl Hydrocarbon Receptor
    Traboulsi, Hussein
    de Souza, Angela Rico
    Allard, Benoit
    Haidar, Zahraa
    Sorin, Mark
    Moarbes, Vanessa
    Fixman, Elizabeth D.
    Martin, James G.
    Eidelman, David H.
    Baglole, Carolyn J.
    FRONTIERS IN PHYSIOLOGY, 2021, 12
12345