Synthesis of (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]diazepine-5,10-diones

被引：0

作者：

Fedorov A.E. ^{[1
]}

Rodinovskaya L.A. ^{[1
]}

Shestopalov A.M. ^{[1
]}

Sigeev A.S. ^{[2
]}

机构：

[1] N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., Moscow

[2] A N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, Moscow

来源：

Russian Chemical Bulletin | 2021年 / 70卷 / 2期

关键词：

combinatorial synthesis; domino reactions; thieno[2,3-e][1,4]diazepinediones; Thorp—Ziegler cyclization;

D O I：

10.1007/s11172-021-3099-1

中图分类号：

学科分类号：

摘要：

A convenient method was developed for the combinatorial synthesis of substituted (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]-diazepine-5,10-diones. The structure and the most probable conformation of (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]diazepine-5,10-dione in solution was established by NMR spectroscopy and calculations using the Gaussian program. © 2021, Springer Science+Business Media LLC.

引用

页码：394 / 405

页数：11

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