Synthesis of (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]diazepine-5,10-diones

被引：0
|
作者：
Fedorov A.E. [1 ]
Rodinovskaya L.A. [1 ]
Shestopalov A.M. [1 ]
Sigeev A.S. [2 ]
机构：
[1] N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., Moscow
[2] A N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, Moscow
来源：
Russian Chemical Bulletin | 2021年 / 70卷 / 2期
关键词：
combinatorial synthesis; domino reactions; thieno[2,3-e][1,4]diazepinediones; Thorp—Ziegler cyclization;
D O I：
10.1007/s11172-021-3099-1
中图分类号：
学科分类号：
摘要：
A convenient method was developed for the combinatorial synthesis of substituted (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]-diazepine-5,10-diones. The structure and the most probable conformation of (5aS)-2-benzylthio-3-cyano-4,5a,6,7,8,10-hexahydro-5H-pyrrolo[1,2-a]thieno[3,2-e][1,4]diazepine-5,10-dione in solution was established by NMR spectroscopy and calculations using the Gaussian program. © 2021, Springer Science+Business Media LLC.
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页码：394 / 405
页数：11
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