Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

被引：0
|
作者：
Akiko Doi
In-Hyun Park
Bo Wen
Peter Murakami
Martin J Aryee
Rafael Irizarry
Brian Herb
Christine Ladd-Acosta
Junsung Rho
Sabine Loewer
Justine Miller
Thorsten Schlaeger
George Q Daley
Andrew P Feinberg
机构：
[1] Johns Hopkins University School of Medicine,Center for Epigenetics and Department of Medicine
[2] Children's Hospital Boston and Howard Hughes Medical Institute,Division of Pediatric Hematology/Oncology
[3] Johns Hopkins Bloomberg School of Public Health,Department of Biostatistics
[4] Sidney Kimmel Comprehensive Cancer Center,undefined
[5] Johns Hopkins University,undefined
来源：
Nature Genetics | 2009年 / 41卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Andrew Feinberg and colleagues show that differential methylation of CpG island shores distinguish human induced pluripotent stem cells from the fibroblasts from which they were derived. These differentially methylated regions of the genome can also distinguish normal colon tissue from colorectal cancer.
引用
收藏
页码：1350 / 1353
页数：3
相关论文
共 50 条
  • [31] Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
    Kim, Jong Hyun
    Kim, Hyung Woo
    Cha, Kyoung Je
    Han, Jiyou
    Jang, Yu Jin
    Kim, Dong Sung
    Kim, Jong-Hoon
    ACS NANO, 2016, 10 (03) : 3342 - 3355
  • [32] Directed differentiation of human embryonic stem cells and induced pluripotent stem cells to functional osteoclasts
    Grigoriadis, A. E.
    Kennedy, M.
    Bozec, A.
    Stenbeck, G.
    Wagner, E. F.
    Keller, G.
    BONE, 2009, 44 (02) : S216 - S216
  • [33] Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes A Methods Overview
    Mummery, Christine L.
    Zhang, Jianhua
    Ng, Elizabeth S.
    Elliott, David A.
    Elefanty, Andrew G.
    Kamp, Timothy J.
    CIRCULATION RESEARCH, 2012, 111 (03) : 344 - 358
  • [34] Banking Human Induced Pluripotent Stem Cells: Lessons Learned from Embryonic Stem Cells?
    Stacey, Glyn N.
    Crook, Jeremy M.
    Hei, Derek
    Ludwig, Tenneille
    CELL STEM CELL, 2013, 13 (04) : 385 - 388
  • [35] Human motor neuron generation from embryonic stem cells and induced pluripotent stem cells
    Nizzardo, M.
    Simone, C.
    Falcone, M.
    Locatelli, F.
    Riboldi, G.
    Comi, G. P.
    Corti, S.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2010, 67 (22) : 3837 - 3847
  • [36] The Involvement of DNA Methylation and Histone Modification on the Epigenetic Regulation of Embryonic Stem Cells and Induced Pluripotent Stem Cells
    Leung, Kenneth Siu-Sing
    Cheng, Vincent Wing-Sang
    Mok, Simon Wing-Fai
    Tsui, Stephen Kwok-Wing
    CURRENT STEM CELL RESEARCH & THERAPY, 2014, 9 (05) : 388 - 395
  • [37] Differentiation of human induced pluripotent stem cells into dermal fibroblasts
    Itoh, M.
    Christiano, A. M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012, 132 : S140 - S140
  • [38] Induction of Human Embryonic and Induced Pluripotent Stem Cells Into Urothelium
    Osborn, Stephanie L.
    Thangappan, Ravikumar
    Luria, Ayala
    Lee, Justin H.
    Nolta, Jan
    Kurzrock, Eric A.
    STEM CELLS TRANSLATIONAL MEDICINE, 2014, 3 (05) : 610 - 619
  • [39] Human embryonic and induced pluripotent stem cells in clinical trials
    Ilic, Dusko
    Devito, Liani
    Miere, Cristian
    Codognotto, Stefano
    BRITISH MEDICAL BULLETIN, 2015, 116 (01) : 19 - 27
  • [40] DNA methylation dynamics in human induced pluripotent stem cells
    Koichiro Nishino
    Akihiro Umezawa
    Human Cell, 2016, 29 : 97 - 100
12345