Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

被引：0

作者：

Akiko Doi

In-Hyun Park

Bo Wen

Peter Murakami

Martin J Aryee

Rafael Irizarry

Brian Herb

Christine Ladd-Acosta

Junsung Rho

Sabine Loewer

Justine Miller

Thorsten Schlaeger

George Q Daley

Andrew P Feinberg

机构：

[1] Johns Hopkins University School of Medicine,Center for Epigenetics and Department of Medicine

[2] Children's Hospital Boston and Howard Hughes Medical Institute,Division of Pediatric Hematology/Oncology

[3] Johns Hopkins Bloomberg School of Public Health,Department of Biostatistics

[4] Sidney Kimmel Comprehensive Cancer Center,undefined

[5] Johns Hopkins University,undefined

来源：

Nature Genetics | 2009年 / 41卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Andrew Feinberg and colleagues show that differential methylation of CpG island shores distinguish human induced pluripotent stem cells from the fibroblasts from which they were derived. These differentially methylated regions of the genome can also distinguish normal colon tissue from colorectal cancer.

引用

页码：1350 / 1353

页数：3

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