Adenine and uracil derivatives with antitubercular activity

被引：0
|
作者：
Alksnis E. [1 ]
Korneeva D. [1 ]
Lukevics E. [1 ]
机构：
[1] Latvian Institute of Organic Synthesis
来源：
Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 6期
关键词：
Alkylation; Purines; Pyrimidines; Tuberculosis;
D O I：
10.1023/A:1011973514672
中图分类号：
学科分类号：
摘要：
We have carried out the synthesis and investigated the antitubercular activity of adenine and 5-fluorouracil derivatives. It was found that a comparatively large, lipophilic fragment is needed in the active molecule to inhibit the tuberculosis pathogen.
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收藏
页码：743 / 746
页数：3
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