Preparation and in Vitro/in Vivo Evaluation of Insulin-Loaded Poly(Acryloyl-Hydroxyethyl Starch)-PLGA Composite Microspheres

被引:0
|
作者
Ge Jiang
Wei Qiu
Patrick P. DeLuca
机构
[1] University of Kentucky ,Pharmaceutical Sciences
[2] College of Pharmacy,undefined
来源
Pharmaceutical Research | 2003年 / 20卷
关键词
PLGA; hydroxyethyl starch; microsphere; insulin; controlled release;
D O I
暂无
中图分类号
学科分类号
摘要
Purpose. The purpose of this study was to develop and evaluate a novel composite microsphere delivery system composed of poly(D,L-lactide-co-glycolide) (PLGA) and poly(acryloyl hydroxyethyl starch) (acryloyl derivatized HES; AcHES) hydrogel using bovine insulin as a model therapeutic protein.
引用
收藏
页码:452 / 459
页数:7
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