共 50 条
- [1] Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins[J]. NATURE, 2015, 526 (7571) : 136 - +Bondy-Denomy, Joseph论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, CanadaGarcia, Bianca论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Rollins, MaryClare F.论文数: 0 引用数: 0 h-index: 0机构: Montana State Univ, Dept Microbiol & Immunol, Bozeman, MT 59717 USA Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, CanadaHidalgo-Reyes, Yurima论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, CanadaWiedenheft, Blake论文数: 0 引用数: 0 h-index: 0机构: Montana State Univ, Dept Microbiol & Immunol, Bozeman, MT 59717 USA Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, CanadaMaxwell, Karen L.论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, CanadaDavidson, Alan R.论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada Univ Toronto, Dept Biochem, Toronto, ON M5S 1A8, Canada Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada
- [2] Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type II Anti-CRISPR Proteins[J]. JOURNAL OF MOLECULAR BIOLOGY, 2023, 435 (07)论文数: 引用数: h-index:机构:Maxwell, Karen L.论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Dept Biochem, 661 Univ Ave,Suite 1600, Toronto, ON M5G 1M1, Canada Univ Toronto, Dept Biochem, 661 Univ Ave,Suite 1600, Toronto, ON M5G 1M1, Canada
- [3] Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins[J]. MOLECULAR CELL, 2019, 74 (02) : 296 - +论文数: 引用数: h-index:机构:Gao, Ang论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, Dept Biochem & Mol Pharmacol, New York, NY 10016 USA Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China论文数: 引用数: h-index:机构:Wang, Yong论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R ChinaFeng, Han论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R ChinaLiu, Songqing论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R ChinaGao, Guangxia论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Inst Biophys, CAS Ctr Excellence Biomacromol, CAS Key Lab Infect & Immun, Beijing 100101, Peoples R China Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R ChinaSerganov, Alexander论文数: 0 引用数: 0 h-index: 0机构: NYU, Sch Med, Dept Biochem & Mol Pharmacol, New York, NY 10016 USA Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R ChinaGao, Pu论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, CAS Key Lab Infect & Immun,CAS Ctr Excellence Bio, Beijing 100101, Peoples R China
- [4] Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins[J]. CELL HOST & MICROBE, 2019, 25 (06) : 815 - +Zhang, Heng论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USALi, Zhuang论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USADaczkowski, Courtney M.论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biochem, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USAGabel, Clinton论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USAMesecar, Andrew D.论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA Purdue Univ, Dept Biochem, W Lafayette, IN 47907 USA Purdue Univ, Ctr Canc Res, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USAChang, Leifu论文数: 0 引用数: 0 h-index: 0机构: Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA Purdue Univ, Ctr Canc Res, W Lafayette, IN 47907 USA Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA
- [5] Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9[J]. Nature Methods, 2018, 15 : 924 - 927Felix Bubeck论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Mareike D. Hoffmann论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Zander Harteveld论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Sabine Aschenbrenner论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Andreas Bietz论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Max C. Waldhauer论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Kathleen Börner论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Julia Fakhiri论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Carolin Schmelas论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Laura Dietz论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Dirk Grimm论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Bruno E. Correia论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Roland Eils论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)Dominik Niopek论文数: 0 引用数: 0 h-index: 0机构: University of Heidelberg,Synthetic Biology Group, Institute for Pharmacy and Biotechnology (IPMB) and Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant)
- [6] Anti-CRISPR proteins: Counterattack of phages on bacterial defense (CRISPR/Cas) system[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 233 (01) : 57 - 59Chaudhary, Kulbhushan论文数: 0 引用数: 0 h-index: 0机构: Indian Agr Res Inst, Div Plant Pathol, Adv Ctr Plant Virol, New Delhi 110012, India Indian Agr Res Inst, Div Plant Pathol, Adv Ctr Plant Virol, New Delhi 110012, IndiaChattopadhyay, Anirudha论文数: 0 引用数: 0 h-index: 0机构: SD Agr Univ, Dept Plant Pathol, CP Coll Agr, S K Nagar, Gujrat, India Indian Agr Res Inst, Div Plant Pathol, Adv Ctr Plant Virol, New Delhi 110012, IndiaPratap, Dharmendra论文数: 0 引用数: 0 h-index: 0机构: Chaudhary Charan Singh Univ, Dept Genet & Plant Breeding, Meerut, Uttar Pradesh, India Indian Agr Res Inst, Div Plant Pathol, Adv Ctr Plant Virol, New Delhi 110012, India
- [7] Engineered Anti-CRISPR Proteins for Precision Control of CRISPR-Cas9[J]. MOLECULAR THERAPY, 2019, 27 (04) : 297 - 297Bubeck, Felix论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyHoffmann, Mareike D.论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyHarteveld, Zander论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Inst Bioengn, Lausanne, Switzerland SIB, Lausanne, Switzerland Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyAschenbrenner, Sabine论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyBietz, Andreas论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyNotbohm, Judith论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany论文数: 引用数: h-index:机构:Mathony, Jan论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyWaldhauer, Max C.论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyDietz, Laura论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyBoerner, Kathleen论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Univ Hosp Heidelberg, Dept Infect Dis, Virol, Heidelberg, Germany Heidelberg Univ, Cluster Excellence CellNetworks, Heidelberg, Germany German Ctr Infect Res DZIF, Partner Site Heidelberg, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyFakhiri, Julia论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Univ Hosp Heidelberg, Dept Infect Dis, Virol, Heidelberg, Germany Heidelberg Univ, Cluster Excellence CellNetworks, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Correia, Bruno E.论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Inst Bioengn, Lausanne, Switzerland SIB, Lausanne, Switzerland Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyEils, Roland论文数: 0 引用数: 0 h-index: 0机构: BIH, Digital Hlth Ctr, Berlin, Germany Charite, Berlin, Germany Univ Hosp Heidelberg, Hlth Data Sci Unit, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, GermanyNiopek, Dominik论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Synthet Biol Grp, Inst Pharm & Biotechnol IPMB, Heidelberg, Germany
- [8] Engineered anti-CRISPR proteins for optogenetic control of CRISPR-Cas9[J]. NATURE METHODS, 2018, 15 (11) : 924 - +Bubeck, Felix论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyHoffmann, Mareike D.论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyHarteveld, Zander论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Inst Bioengn, Lausanne, Switzerland Swiss Inst Bioinformat, Lausanne, Switzerland Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyAschenbrenner, Sabine论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyBietz, Andreas论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyWaldhauer, Max C.论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyBoerner, Kathleen论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Heidelberg, Dept Infect Dis, Virol, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Cluster Excellence CellNetworks, Heidelberg, Germany German Ctr Infect Res DZIF, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyFakhiri, Julia论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp Heidelberg, Dept Infect Dis, Virol, Heidelberg, Germany Heidelberg Univ, BioQuant Ctr, Heidelberg, Germany Heidelberg Univ, Cluster Excellence CellNetworks, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany论文数: 引用数: h-index:机构:Dietz, Laura论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany论文数: 引用数: h-index:机构:Correia, Bruno E.论文数: 0 引用数: 0 h-index: 0机构: Ecole Polytech Fed Lausanne, Inst Bioengn, Lausanne, Switzerland Swiss Inst Bioinformat, Lausanne, Switzerland Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyEils, Roland论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Berlin Inst Hlth, Digital Hlth Ctr, Berlin, Germany Charite, Berlin, Germany Univ Hosp Heidelberg, Hlth Data Sci Unit, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, GermanyNiopek, Dominik论文数: 0 引用数: 0 h-index: 0机构: Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany Heidelberg Univ, Ctr Quantitat Anal Mol & Cellular Biosyst BioQuan, Heidelberg, Germany German Canc Res Ctr, Dept Theoret Bioinformat, Heidelberg, Germany Heidelberg Univ, Inst Pharm & Biotechnol IPMB, Synthet Biol Grp, Heidelberg, Germany
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