Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

被引：0

作者：

Joseph Bondy-Denomy

Bianca Garcia

Scott Strum

Mingjian Du

MaryClare F. Rollins

Yurima Hidalgo-Reyes

Blake Wiedenheft

Karen L. Maxwell

Alan R. Davidson

机构：

[1] University of Toronto,Department of Molecular Genetics

[2] University of Toronto,Department of Biochemistry

[3] Montana State University,Department of Microbiology and Immunology

[4] Donnelly Centre for Cellular and Biomolecular Research,undefined

[5] University of Toronto,undefined

[6] †Present address: Department of Microbiology and Immunology,undefined

[7] University of California,undefined

[8] San Francisco,undefined

[9] San Francisco,undefined

[10] California 94158,undefined

[11] USA.,undefined

来源：

Nature | 2015年 / 526卷

关键词：

D O I：

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学科分类号：

摘要：

Bacterial cells evolved an immune system known as CRISPR–Cas to protect themselves from viral infection, triggering viruses to evolve anti-CRISPR proteins; here, three anti-CRISPR proteins are characterized, with each one interfering with the host CRISPR system at a different point.

引用

页码：136 / 139

页数：3

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