Genetics of IL28B and HCV—response to infection and treatment

被引：0

作者：

C. Nelson Hayes

Michio Imamura

Hiroshi Aikata

Kazuaki Chayama

机构：

[1] Applied Life Sciences,Department of Gastroenterology and Metabolism

[2] Institute of Biomedical and Health Sciences,undefined

[3] Hiroshima University,undefined

来源：

Nature Reviews Gastroenterology & Hepatology | 2012年 / 9卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The role ofIL28B in chronic HCV infection has been studied extensively since a series of genome-wide association studies linked the IL28B locus to response to HCV therapy. In this Review, the authors provide a summary of the role of IL28B in HCV infection, describing how IL28Bgenetics affect viral dynamics, host immune response to the virus and response to therapy.

引用

页码：406 / 417

页数：11

共 50 条

[41] FEMALE SEX AND VARIATIONS IN IL28B ARE INDEPENDENTLY ASSOCIATED WITH SPONTANEOUS CLEARANCE OF ACUTE HCV INFECTION
Grebely, J.
Dore, G. J.
van der Loeff, M. Schim
Rice, T.
Cox, A. L.
Bruneau, J.
Kim, A. Y.
George, J.
Maher, L.
Lloyd, A. R.
Hellard, M.
Page, K.
Prins, M.
JOURNAL OF HEPATOLOGY, 2012, 56 : S348 - S348
[42] In the Absence of HCV Infection, Interferon Stimulated Gene Expression in Liver Is Not Associated With IL28B Genotype
Shebl, Fatma M.
Maeder, Dennis
Shao, Yongwu
Prokunina-Olsson, Ludmila
Schadt, Eric E.
O'Brien, Thomas R.
GASTROENTEROLOGY, 2010, 139 (04) : 1422 - 1424
[43] IL28B Genetic Variation and Treatment Response in Patients with Hepatitis C Virus Genotype 3 Infection
Moghaddam, Amir
Melum, Espen
Reinton, Nils
Ring-Larsen, Helmer
Verbaan, Hans
Bjoro, Kristian
Dalgard, Olav
HEPATOLOGY, 2011, 53 (03) : 746 - 754
[44] IL28B polymorphisms predict the response to chronic hepatitis C virus infection treatment in a Mexican population
Martinez-Gomez, Laura E.
Chavez-Tapia, Norberto C.
Burguete-Garcia, Ana I.
Aguilar-Olivos, Nancy
Madrid-Marina, Vicente
Roman-Bahena, Margarita
Orbe-Orihuela, Citlalli
Misael, Uribe
Mendez-Sanchez, Nahum
ANNALS OF HEPATOLOGY, 2012, 11 (06) : 876 - 881
[45] The Effect of IL28B Gene Polymorphism on Treatment Response in Iranian Patients with Hepatitis C Virus Infection
Zare, Fateme
Hadinedoushan, Hossein
Meybodi, Mohsen Akhondi
Dehghanmanshadi, Mahdi
Bafghi, Seyyed Ali Mirghanizade
Vakili, Mahmood
JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2016, 9 (12) : 1 - 6
[46] Impact of IL28B Polymorphisms on Sustained Virological Response of HCV-HIV-coinfected Patients
Bachmann, H.
Siffert, W.
Skaletz-Rorowski, A.
Jansen, K.
Moll, A.
Dupke, S.
Koeppe, S.
Harrer, T.
Rausch, M.
Brockmeyer, N.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2011, 383 : 53 - 53
[47] IL28B polymorphisms and treatment of hepatitis C
Clark P.J.
Thompson A.J.V.
Muir A.J.
Current Hepatitis Reports, 2011, 10 (1) : 70 - 78
[48] LECT2 specifically induced by IL28B regulates interferon response and HCV replication
Shirasaki, Takayoshi
Honda, Masao
Shimakami, Tetsuro
Murai, Kazuhisa
Shiomoto, Takayuki
Misu, Hirofumi
Takamura, Toshinari
Lemon, Stanley M.
Murakami, Seishi
Kaneko, Shuichi
HEPATOLOGY, 2014, 60 : 1054A - 1054A
[49] Role of IL28B Gene Polymorphisms in Response to the Standard of Care Treatment in Egyptian Patients with Chronic HCV Genotype Four
Hendy, Olfat M.
Abd El Moneam, Elhamy
Al Shafie, Mona A.
El-Sabawy, Maha
Rady, Mohammed A.
El Baz, Sherif A.
LIFE SCIENCE JOURNAL-ACTA ZHENGZHOU UNIVERSITY OVERSEAS EDITION, 2011, 8 (04): : 908 - 915
[50] IL28B polymorphisms of both recipient and donor cooperate to influence IFN treatment response in HCV recurrence after liver transplantation, but IL28B SNPs of the recipient play a major role in IFN-induced blocking of HCV replication
Barbera, Floriana
Russelli, Giovanna
Pipitone, Loredana
Pietrosi, Giada
Corsale, Sveva
Vizzini, Giovanni
Gridelli, Bruno
Conaldi, Pier Giulio
NEW MICROBIOLOGICA, 2015, 38 (02): : 201 - 210

← 1 2 3 4 5 →