Genetics of IL28B and HCV—response to infection and treatment

被引：0

作者：

C. Nelson Hayes

Michio Imamura

Hiroshi Aikata

Kazuaki Chayama

机构：

[1] Applied Life Sciences,Department of Gastroenterology and Metabolism

[2] Institute of Biomedical and Health Sciences,undefined

[3] Hiroshima University,undefined

来源：

Nature Reviews Gastroenterology & Hepatology | 2012年 / 9卷

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摘要：

The role ofIL28B in chronic HCV infection has been studied extensively since a series of genome-wide association studies linked the IL28B locus to response to HCV therapy. In this Review, the authors provide a summary of the role of IL28B in HCV infection, describing how IL28Bgenetics affect viral dynamics, host immune response to the virus and response to therapy.

引用

页码：406 / 417

页数：11

共 50 条

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