Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

被引：0

作者：

K. Højlund

J. F. P. Wojtaszewski

J. Birk

B. F. Hansen

H. Vestergaard

H. Beck-Nielsen

机构：

[1] Odense University Hospital,Diabetes Research Centre, Department of Endocrinology

[2] University of Copenhagen,Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology

[3] Novo Nordisk,Diabetes Biology

[4] University of Copenhagen,Department of Endocrinology, Herlev Hospital

[5] Odense University Hospital,Department of Endocrinology

来源：

Diabetologia | 2006年 / 49卷

关键词：

Glucose metabolism; Glycogen synthase; Insulin clearance; Insulin receptor mutation; Insulin signalling;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：1827 / 1837

页数：10

共 50 条

[41] Dominant transmission of insulin resistance in a type A family resulting from a heterozygous nonsense mutation in the insulin receptor gene and associated with decreased mRNA level and insulin binding sites
Magre, J
Karayanni, C
Hadjiathanasiou, CG
DesboisMouthon, C
Meier, M
Vigouroux, C
Stavrinadis, C
Sinaniotis, C
Caron, M
Capeau, J
DIABETES, 1997, 46 (11) : 1901 - 1903
[42] Case Report: A Chinese Family of Type A Insulin Resistance Syndrome With Diabetes Mellitus, With a Novel Heterozygous Missense Mutation of the Insulin Receptor Gene
You, Wei
Yang, Jianming
Wang, Lu
Liu, Yanqun
Wang, Wen
Zhu, Li
Wang, Wei
Yang, Jun
Chen, Fangyuan
FRONTIERS IN ENDOCRINOLOGY, 2022, 13
[43] Heterozygous insulin receptor knockout mice are glucocompetent but have hypertension and impaired insulin stimulated nitric oxide release
Wheatcroft, S
Crossey, P
Shah, A
Norhona, B
Kearney, M
ATHEROSCLEROSIS, 2003, 170 (01) : S12 - S12
[44] CHARACTERIZATION OF SKELETAL-MUSCLE INSULIN-RECEPTOR
DUBLER, RE
WHIPPLE, JH
LARNER, J
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1985, 236 (01) : 119 - 129
[45] Skeletal muscle glucocorticoid receptor density and insulin resistance
Reynolds, RM
Chapman, KE
Seckl, JR
Walker, BR
McKeigue, PM
Lithell, HO
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (19): : 2505 - 2506
[46] Impaired Insulin Signaling in the Endothelial Cells Reduces Insulin-Induced Glucose Uptake by the Skeletal Muscle
Kubota, Naoto
Kubota, Tetsuya
Kumagai, Hiroki
Inoue, Mariko
Yamauchi, Toshimasa
Ueki, Kohjiro
Kadowaki, Takashi
DIABETES, 2011, 60 : A91 - A92
[47] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle
Kubota, Naoto
Kubota, Tetsuya
Kadowaki, Takashi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, 118 : 34P - 34P
[48] Diazoxide-unresponsive Hyperinsulinemic Hypoglycaemia in a Preterm Infant with Heterozygous Insulin Receptor Gene Mutation
Poon, Sarah Wing-Yiu
Chung, Brian Hon-Yin
Wong, Mabel Siu-Chun
Tsang, Anita Man-Ching
JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 2025, 17 (01) : 115 - 119
[49] Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle
Kubota, Tetsuya
Kubota, Naoto
Kumagai, Hiroki
Yamaguchi, Shinichi
Kozono, Hideki
Takahashi, Takehiro
Inoue, Mariko
Itoh, Shinsuke
Takamoto, Iseki
Sasako, Takayoshi
Kumagai, Katsuyoshi
Kawai, Tomoko
Hashimoto, Shinji
Kobayashi, Tsuneo
Sato, Maki
Tokuyama, Kumpei
Nishimura, Satoshi
Tsunoda, Masaki
Ide, Tomohiro
Murakami, Koji
Yamazaki, Tomomi
Ezaki, Osamu
Kawamura, Koichi
Masuda, Hirotake
Moroi, Masao
Sugi, Kaoru
Oike, Yuichi
Shimokawa, Hiroaki
Yanagihara, Nobuyuki
Tsutsui, Masato
Terauchi, Yasuo
Tobe, Kazuyuki
Nagai, Ryozo
Kamata, Katsuo
Inoue, Kenji
Kodama, Tatsuhiko
Ueki, Kohjiro
Kadowaki, Takashi
CELL METABOLISM, 2011, 13 (03) : 294 - 307
[50] Insulin-Stimulated ROCK1 Activity Is Impaired in Skeletal Muscle of Insulin Resistant Subjects
Chun, Kwang-Hoon
Lee, Dae Ho
Jung, Yunshin
Ciaraldi, Theodore P.
Kim, Young-Bum
DIABETES, 2010, 59 : A60 - A60

← 1 2 3 4 5 →