Partial rescue of in vivo insulin signalling in skeletal muscle by impaired insulin clearance in heterozygous carriers of a mutation in the insulin receptor gene

被引：0
|
作者：
K. Højlund
J. F. P. Wojtaszewski
J. Birk
B. F. Hansen
H. Vestergaard
H. Beck-Nielsen
机构：
[1] Odense University Hospital,Diabetes Research Centre, Department of Endocrinology
[2] University of Copenhagen,Copenhagen Muscle Research Centre, Institute of Exercise and Sport Sciences, Department of Human Physiology
[3] Novo Nordisk,Diabetes Biology
[4] University of Copenhagen,Department of Endocrinology, Herlev Hospital
[5] Odense University Hospital,Department of Endocrinology
来源：
Diabetologia | 2006年 / 49卷
关键词：
Glucose metabolism; Glycogen synthase; Insulin clearance; Insulin receptor mutation; Insulin signalling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1827 / 1837
页数：10
相关论文
共 50 条
  • [21] Doxorubicin leads to impaired insulin signaling in skeletal muscle
    de Lima Junior, Edson Alves
    de Souza, Camila Oliveira
    de Souza Teixeira, Alexandre Abilio
    Batatinha, Helena Angelica
    Lira, Fabio de Santos
    Rosa Neto, Jose Cesar
    CANCER & METABOLISM, 2014, 2
  • [22] Resistance to type A insulin: A new mutation of the receptor gene of the insulin described
    Lopez Alaminos, Maria Elena
    Alvarado Rosas, Karol Almendra
    Martinez Garcia, Maria
    Trincado Aznar, Pablo
    Alvarez Ballano, Diego
    ENDOCRINOLOGIA DIABETES Y NUTRICION, 2020, 67 (09): : 611 - 612
  • [23] Intensive Insulin Treatment in a Patient with Type A Insulin Resistance Syndrome Associated with a Novel Heterozygous Mutation of Trp1120Gly in the Insulin Receptor Gene
    Yang, Yu
    Huang, Zhimin
    Wei, Guohong
    Li, Yueli
    Deng, Wanping
    Li, Yanbing
    DIABETES, 2021, 70
  • [24] Doxorubicin leads to impaired insulin signaling in skeletal muscle
    Edson Alves de Lima
    Camila Oliveira de Souza
    Alexandre Abílio de Souza Teixeira
    Helena Angélica Batatinha
    Fábio de Santos Lira
    José César Rosa Neto
    Cancer & Metabolism, 2 (Suppl 1)
  • [25] Partial rescue of insulin receptor-deficient mice by transgenic complementation with an activated insulin receptor in the liver
    Baudry, A
    Jackerott, M
    Lamothe, B
    Kozyrev, SV
    Leroux, L
    Durel, B
    Saint-Just, S
    Joshi, RL
    GENE, 2002, 299 (1-2) : 219 - 225
  • [26] A case report of hyperinsulinemic hypoglycemia caused by a heterozygous novel mutation in the insulin receptor gene
    Ozgen, Ilker Tolga
    Bahar, Semra
    Uyanik, Bulent
    HORMONE RESEARCH IN PAEDIATRICS, 2022, 95 (SUPPL 2): : 261 - 262
  • [27] The Insulin Receptor Mediates Insulin's Early Plasma Clearance by Liver, Muscle, and Kidney
    Meijer, Rick I.
    Barrett, Eugene J.
    BIOMEDICINES, 2021, 9 (01) : 1 - 17
  • [28] Insulin regulation of skeletal muscle PDK4 expression is impaired in insulin resistant states
    Kim, YI
    Lee, FN
    Choi, WS
    Youn, JH
    DIABETES, 2005, 54 : A327 - A327
  • [29] Novel mutation in insulin receptor gene identified after muscle biopsy in a Niuean woman with severe insulin resistance
    Murphy, R.
    Smith, G.
    Isaac, I.
    Hutchinson, D.
    Semple, R. K.
    DIABETIC MEDICINE, 2015, 32 (10) : E24 - E28
  • [30] Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle
    Laine, H
    Knuuti, MJ
    Ruotsalainen, U
    Raitakari, M
    Iida, H
    Kapanen, J
    Kirvelä, O
    Haaparanta, M
    Yki-Järvinen, H
    Nuutila, P
    JOURNAL OF HYPERTENSION, 1998, 16 (02) : 211 - 219
12345