Aminomethylation of Quercetin by Tetrahydroisoquinoline Derivatives and Their Biological Activity

被引：0
|
作者：
Sh. N. Zhurakulov
D. A. Narbutaeva
A. M. Karakulova
F. M. Tursunkhodzhaeva
V. I. Vinogradova
机构：
[1] Academy of Sciences of the Republic of Uzbekistan,S. Yu. Yunusov Institute of the Chemistry of Plant Substances
[2] Mirzo Ulugbek National University of Uzbekistan,undefined
来源：
Chemistry of Natural Compounds | 2023年 / 59卷
关键词：
quercetin; 1-aryltetrahydroisoquinolines; aminomethylation reaction; hypoxia;
D O I：
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学科分类号：
摘要：
Monosubstituted quercetin conjugates were synthesized via Mannich reactions from 1-aryl-(or H)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines in 75–96% yields. Compounds with antihypoxic activity more effective than that of quercetin were found among them.
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页码：655 / 661
页数：6
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