Aminomethylation of Uracil and 6-Methyluracil by 3,4-dimethoxyphenylethylamine and Tetrahydroisoquinoline Derivatives

被引：0

作者：

Zhurakulov, Sh. N. ^{[1
,2
]}

Rakhimov, Sh. B. ^{[1
]}

Kodirov, M. A. ^{[1
]}

Vinogradova, V. I. ^{[1
]}

Sagdullaev, Sh. Sh. ^{[1
]}

机构：

[1] Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Tashkent 100170, Uzbekistan

[2] Natl Univ Uzbekistan, Tashkent 100174, Uzbekistan

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 02期

关键词：

uracil; 6-methyluracil; 3; 4-dimethoxyphenylethylamine; 1-aryltetrahydroisoquinolines; formalin; Mannich reaction;

D O I：

10.1007/s10600-023-03987-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The Mannich reactions of uracil and 6-methyluracil with homoveratrylamine and 1-aryltetrahydroisoquinolines in EtOH and dioxane were studied. 5-[(2-Hydroxymethyl)-4,5-dimethoxyphenylethylamino)methyl]-6-methylpyrimidine-2,4(1H, 3H)-dione was formed in EtOH in addition to the usual products (in dioxane).

引用

页码：331 / 335

页数：5

共 50 条

[1] Aminomethylation of Uracil and 6-Methyluracil by 3,4-dimethoxyphenylethylamine and Tetrahydroisoquinoline Derivatives
Sh.N. Zhurakulov
Sh.B. Rakhimov
M. A. Kodirov
V. I. Vinogradova
Sh.Sh. Sagdullaev
Chemistry of Natural Compounds, 2023, 59 : 331 - 335
[2] 3,4-DIMETHOXYPHENYLETHYLAMINE IN SCHIZOPHRENIA
WILLIAMS, CH
GIBSON, JG
MCCORMIC.WO
NATURE, 1966, 211 (5054) : 1195 - &
[3] ELECTROCATALYTIC SYNTHESIS OF 3,4-DIMETHOXYPHENYLETHYLAMINE
TUSUPBEKOVA, GK
KIRILYUS, IV
KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1985, 19 (02): : 204 - 206
[4] EXCRETION OF 3,4-DIMETHOXYPHENYLETHYLAMINE IN SCHIZOPHRENIA
VONSTUDNITZ, W
NYMAN, GE
ACTA PSYCHIATRICA SCANDINAVICA, 1965, 41 (01) : 117 - 121
[5] EFFECTS OF 3,4-DIMETHOXYPHENYLETHYLAMINE IN MAN
HOLLISTER, LE
FRIEDHOFF, AJ
NATURE, 1966, 210 (5043) : 1377 - +
[6] CRYSTAL STRUCTURES OF DIMERS OF URACIL AND 6-METHYLURACIL
KONNERT, J
GIBSON, JW
KARLE, IL
KHATTAK, MN
WANG, SY
NATURE, 1970, 227 (5261) : 953 - &
[7] SYNTHESIS OF URACIL, 6-METHYLURACIL AND SOME DIHYDROURACILS
BHAT, KS
RAO, AS
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1983, 15 (05) : 303 - 313
[8] RADIOIMMUNOLOGICAL DETERMINATION OF 3,4-DIMETHOXYPHENYLETHYLAMINE IN URINE
KNOLL, E
WISSER, H
CLINICA CHIMICA ACTA, 1976, 68 (03) : 327 - 332
[9] PHARMACOLOGY OF AKINESIA - INVESTIGATIONS ON 3,4-DIMETHOXYPHENYLETHYLAMINE
BARBEAU, A
TETREAULT, L
OLIVA, L
MORAZAIN, L
CARDIN, L
NATURE, 1966, 209 (5024) : 719 - +
[10] PHYSIOLOGICAL DISPOSITION AND METABOLISM OF 3,4-DIMETHOXYPHENYLETHYLAMINE IN RAT
VOGEL, WH
INTERNATIONAL JOURNAL OF NEUROPHARMACOLOGY, 1968, 7 (04): : 373 - &

← 1 2 3 4 5 →