The Presence of a Fibrotic Focus in Invasive Breast Carcinoma Correlates with the Expression of Carbonic Anhydrase IX and is a Marker of Hypoxia and Poor Prognosis
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作者:
Cecile G. Colpaert
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机构:University Hospital Antwerp,Department of Pathology
Cecile G. Colpaert
Peter B. Vermeulen
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机构:University Hospital Antwerp,Department of Pathology
Peter B. Vermeulen
Stephen B. Fox
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机构:University Hospital Antwerp,Department of Pathology
Stephen B. Fox
Adrian L. Harris
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机构:University Hospital Antwerp,Department of Pathology
Adrian L. Harris
Luc Y. Dirix
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机构:University Hospital Antwerp,Department of Pathology
Luc Y. Dirix
Eric A. Van Marck
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机构:University Hospital Antwerp,Department of Pathology
Eric A. Van Marck
机构:
[1] University Hospital Antwerp,Department of Pathology
[2] University of Antwerp,Translational Cancer Research Group
[3] AZ Sint-Augustinus,John Radcliffe Hospital
[4] Weatherall Institute of Molecular Medicine,undefined
breast cancer;
carbonic anhydrase IX;
fibrotic focus;
hypoxia;
intra-tumoral fibroblasts;
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摘要:
The value of the fibrotic focus (FF) as a marker of intra-tumoral hypoxia in invasive breast carcinoma was assessed by studying its relationship with the expression of the hypoxia-induced carbonic anhydrase IX (CA IX), angiogenesis indices and prognosis.
机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Kato, Yukihiro
Yashiro, Masakazu
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Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Osaka City Univ, Grad Sch Med, Oncol Inst Geriatr & Med Sci, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Yashiro, Masakazu
Noda, Satoru
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Noda, Satoru
Kashiwagi, Shinichiro
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Kashiwagi, Shinichiro
Matsuoka, Junko
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Matsuoka, Junko
Fuyuhiro, Yuhiko
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Fuyuhiro, Yuhiko
Doi, Yosuke
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
Doi, Yosuke
Hirakawa, Kosei
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机构:Osaka City Univ, Grad Sch Med, Dept Surg Oncol, Abeno Ku, Osaka 5458585, Japan
机构:
Mahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
Univ Glasgow, Wolfson Wohl Canc Res Ctr, Sch Canc Sci, Glasgow City, ScotlandMahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
Numprasit, Warapan
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Yangngam, Supaporn
Prasopsiri, Jaturawitt
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Mahidol Univ, Fac Med, Dept Immunol, Siriraj Hosp, Bangkok, ThailandMahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
Prasopsiri, Jaturawitt
Quinn, Jean A.
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Univ Glasgow, Wolfson Wohl Canc Res Ctr, Sch Canc Sci, Glasgow City, ScotlandMahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
Quinn, Jean A.
Edwards, Joanne
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Univ Glasgow, Wolfson Wohl Canc Res Ctr, Sch Canc Sci, Glasgow City, ScotlandMahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
Edwards, Joanne
Thuwajit, Chanitra
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Mahidol Univ, Fac Med, Dept Immunol, Siriraj Hosp, Bangkok, ThailandMahidol Univ, Siriraj Hosp, Dept Surg, Div Head Neck & Breast Surg,Fac Med, Bangkok, Thailand
机构:
Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Chu, Cheng-Yu
Jin, Yi-Ting
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Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Jin, Yi-Ting
Zhang, Wei
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Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Zhang, Wei
Yu, Juan
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Fudan Univ, Sch Basic Med Sci, Dept Pathol, Shanghai 200032, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Yu, Juan
Yang, Hai-Ping
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Fudan Univ, Sch Basic Med Sci, Dept Pathol, Shanghai 200032, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Yang, Hai-Ping
Wang, Hong-Ying
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Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Wang, Hong-Ying
Zhang, Zi-Jing
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Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Zhang, Zi-Jing
Liu, Xiu-Ping
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Fudan Univ, Sch Basic Med Sci, Dept Pathol, Shanghai 200032, Peoples R China
Fudan Univ, Peoples Hosp Shanghai 5, Dept Pathol, Shanghai 200032, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China
Liu, Xiu-Ping
Zou, Qiang
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Fudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R ChinaFudan Univ, Huashan Hosp, Dept Gen Surg, Shanghai 200040, Peoples R China