The Presence of a Fibrotic Focus in Invasive Breast Carcinoma Correlates with the Expression of Carbonic Anhydrase IX and is a Marker of Hypoxia and Poor Prognosis

被引:0
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作者
Cecile G. Colpaert
Peter B. Vermeulen
Stephen B. Fox
Adrian L. Harris
Luc Y. Dirix
Eric A. Van Marck
机构
[1] University Hospital Antwerp,Department of Pathology
[2] University of Antwerp,Translational Cancer Research Group
[3] AZ Sint-Augustinus,John Radcliffe Hospital
[4] Weatherall Institute of Molecular Medicine,undefined
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关键词
breast cancer; carbonic anhydrase IX; fibrotic focus; hypoxia; intra-tumoral fibroblasts;
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摘要
The value of the fibrotic focus (FF) as a marker of intra-tumoral hypoxia in invasive breast carcinoma was assessed by studying its relationship with the expression of the hypoxia-induced carbonic anhydrase IX (CA IX), angiogenesis indices and prognosis.
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页码:137 / 147
页数:10
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