The Presence of a Fibrotic Focus in Invasive Breast Carcinoma Correlates with the Expression of Carbonic Anhydrase IX and is a Marker of Hypoxia and Poor Prognosis

被引：0
|
作者：
Cecile G. Colpaert
Peter B. Vermeulen
Stephen B. Fox
Adrian L. Harris
Luc Y. Dirix
Eric A. Van Marck
机构：
[1] University Hospital Antwerp,Department of Pathology
[2] University of Antwerp,Translational Cancer Research Group
[3] AZ Sint-Augustinus,John Radcliffe Hospital
[4] Weatherall Institute of Molecular Medicine,undefined
来源：
Breast Cancer Research and Treatment | 2003年 / 81卷
关键词：
breast cancer; carbonic anhydrase IX; fibrotic focus; hypoxia; intra-tumoral fibroblasts;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The value of the fibrotic focus (FF) as a marker of intra-tumoral hypoxia in invasive breast carcinoma was assessed by studying its relationship with the expression of the hypoxia-induced carbonic anhydrase IX (CA IX), angiogenesis indices and prognosis.
引用
收藏
页码：137 / 147
页数：10
相关论文
共 50 条
  • [21] Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer
    Maria Raffaella Ambrosio
    Claudia Di Serio
    Giovanna Danza
    Bruno Jim Rocca
    Alessandro Ginori
    Igor Prudovsky
    Niccolò Marchionni
    Maria Teresa del Vecchio
    Francesca Tarantini
    Diagnostic Pathology, 11
  • [22] Overexpression of Carbonic Anhydrase IX is a Dismal Prognostic Marker in Breast Carcinoma in Egyptian Patients
    Samaka, Rehab M.
    Abd El-Wahed, Moshira M.
    Al Sharaky, Dalia R.
    Shehata, Mohamed A.
    Hegazy, Shaymaa E.
    Aleskandarany, Andmohammed A.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2016, 24 (06) : 405 - 413
  • [23] Hypoxia regulated carbonic anhdrase IX (CA IX) expression is significantly associated with poor survival in patients with invasive breast cancer
    Hussain, Syed A.
    Ganesan, Raji
    Billingham, Lucinda
    Reynolds, Gary
    Murray, Paul
    Pastorek, Jaromir
    James, Nicholas D.
    Spooner, David
    Rea, Daniel W.
    Palmer, Daniel H.
    ANNALS OF ONCOLOGY, 2006, 17 : 61 - 61
  • [24] Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial-mesenchymal transition in hepatocellular carcinoma
    Hyuga, Satoshi
    Wada, Hiroshi
    Eguchi, Hidetoshi
    Otsuru, Toru
    Iwgami, Yoshifumi
    Yamada, Daisaku
    Noda, Takehiro
    Asaoka, Tadafumi
    Kawamot, Koichi
    Gotoh, Kunihito
    Takeda, Yutaka
    Tanemura, Masahiro
    Umeshita, Koji
    Doki, Yuichiro
    Mori, Masaki
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2017, 51 (04) : 1179 - 1190
  • [25] Does Carbonic Anhydrase IX Expression Affect Prognosis and Survival in Renal Cell Carcinoma?
    Kim, B.
    Ha, J.
    Choi, M.
    Jung, H.
    Park, C.
    Kim, C.
    UROLOGY, 2012, 80 (03) : S247 - S247
  • [26] Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density
    Beasley, NJP
    Wykoff, CC
    Watson, PH
    Leek, R
    Turley, H
    Gatter, K
    Pastorek, J
    Cox, GJ
    Ratcliffe, P
    Harris, AL
    CANCER RESEARCH, 2001, 61 (13) : 5262 - 5267
  • [27] Carbonic Anhydrase IX in Tumor Tissue and Plasma of Breast Cancer Patients: Reliable Biomarker of Hypoxia and Prognosis
    Rezuchova, Ingeborg
    Bartosova, Maria
    Belvoncikova, Petra
    Takacova, Martina
    Zatovicova, Miriam
    Jelenska, Lenka
    Csaderova, Lucia
    Meciarova, Iveta
    Pohlodek, Kamil
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (05)
  • [28] Tissue Expression of Carbonic Anhydrase IX Correlates to More Aggressive Phenotype of Basal Cell Carcinoma
    Russo, Daniela
    Varricchio, Silvia
    Ilardi, Gennaro
    Martino, Francesco
    Di Crescenzo, Rosa Maria
    Pignatiello, Sara
    Scalvenzi, Massimiliano
    Costa, Claudia
    Mascolo, Massimo
    Merolla, Francesco
    Staibano, Stefania
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [29] Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
    Finkelmeier, Fabian
    Canli, Ozge
    Peiffer, Kai-Henrik
    Walter, Dirk
    Tal, Andrea
    Koch, Christine
    Pession, Ursula
    Vermehren, Johannes
    Trojan, Joerg
    Zeuzem, Stefan
    Piiper, Albrecht
    Greten, Florian R.
    Grammatikos, Georgios
    Waidmann, Oliver
    PLOS ONE, 2018, 13 (07):
  • [30] Carbonic Anhydrase IX Overexpression is Associated with Diminished Prognosis in Esophageal Cancer and Correlates with Her-2 Expression
    Peter Birner
    Bettina Jesch
    Julia Friedrich
    Martin Riegler
    Johannes Zacherl
    Michael Hejna
    Fritz Wrba
    Andrea Schultheis
    Sebastian F. Schoppmann
    Annals of Surgical Oncology, 2011, 18
12345