Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

被引:0
|
作者
Tadato Ban
Takaya Ishihara
Hiroto Kohno
Shotaro Saita
Ayaka Ichimura
Katsumi Maenaka
Toshihiko Oka
Katsuyoshi Mihara
Naotada Ishihara
机构
[1] Institute of Life Science,Department of Protein Biochemistry
[2] Kurume University,Department of Life Science
[3] Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases,undefined
[4] Laboratory of Biomolecular Science,undefined
[5] Faculty of Pharmaceutical Sciences,undefined
[6] Hokkaido University,undefined
[7] Rikkyo University,undefined
[8] Graduate School of Medical Science,undefined
[9] Kyushu University,undefined
来源
Nature Cell Biology | 2017年 / 19卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Ban et al. show that optic atrophy 1 (OPA1) and cardiolipin mediate mitochondrial fusion. In contrast, a homotypic trans-OPA1 interaction independent of cardiolipin mediates membrane tethering to form mitochondrial cristae.
引用
收藏
页码:856 / 863
页数:7
相关论文
共 50 条
  • [41] Mitochondrial Function: OMA1 and OPA1, the Grandmasters of Mitochondrial Health
    McBride, Heidi
    Soubannier, Vincent
    CURRENT BIOLOGY, 2010, 20 (06) : R274 - R276
  • [42] Mitochondrial Membrane Dynamics-Functional Positioning of OPA1
    Lee, Hakjoo
    Yoon, Yisang
    ANTIOXIDANTS, 2018, 7 (12)
  • [43] Opa1 Is Required for Proper Mitochondrial Metabolism in Early Development
    Rahn, Jennifer J.
    Stackley, Krista D.
    Chan, Sherine S. L.
    PLOS ONE, 2013, 8 (03):
  • [44] OPA1 and MICOS Regulate mitochondrial crista dynamics and formation
    Hu, Chao
    Shu, Li
    Huang, Xiaoshuai
    Yu, Jianglong
    Li, Liuju
    Gong, Longlong
    Yang, Meigui
    Wu, Zhida
    Gao, Zhi
    Zhao, Yungang
    Chen, Liangyi
    Song, Zhiyin
    CELL DEATH & DISEASE, 2020, 11 (10)
  • [45] MUTATIONS IN OPA1 EXPAND THE CLINICAL PHENOTYPE OF MITOCHONDRIAL DISEASE
    Chinnery, P.
    Jackson, M.
    Amati-Bonneau, P.
    Yu-Wai-Man, P.
    Gorman, G.
    Duffey, P.
    Baker, M.
    Zeviani, M.
    Horvath, R.
    Miller, J.
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2010, 81 (11): : E32 - E33
  • [46] Structural mechanism of mitochondrial membrane remodeling by human OPA1
    Aydin, Halil
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 210A - 210A
  • [47] Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
    Li, Meng
    Wang, Ling
    Wang, Yijin
    Zhang, Shaoshi
    Zhou, Guoying
    Lieshout, Ruby
    Ma, Buyun
    Liu, Jiaye
    Qu, Changbo
    Verstegen, Monique M. A.
    Sprengers, Dave
    Kwekkeboom, Jaap
    van der Laan, Luc J. W.
    Cao, Wanlu
    Peppelenbosch, Maikel P.
    Pan, Qiuwei
    CELLS, 2020, 9 (01)
  • [48] Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1
    Ehses, Sarah
    Raschke, Ines
    Mancuso, Giuseppe
    Bernacchia, Andrea
    Geimer, Stefan
    Tondera, Daniel
    Martinou, Jean-Claude
    Westermann, Benedikt
    Rugarli, Elena I.
    Langer, Thomas
    JOURNAL OF CELL BIOLOGY, 2009, 187 (07): : 1023 - 1036
  • [49] Mechanisms of Membrane Remodelling Mediated by Short Form of the Mitochondrial Inner Membrane Fusion Protein OPA1
    Zhang, Danyang
    Yan, Zhang
    Niu, Tongxin
    Egelman, Edward H.
    Sun, Fei
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 615A - 615A
  • [50] Structural mechanism of mitochondrial membrane remodelling by human OPA1
    von der Malsburg, Alexander
    Sapp, Gracie M.
    Zuccaro, Kelly E.
    von Appen, Alexander
    Moss, Frank R.
    Kalia, Raghav
    Bennett, Jeremy A.
    Abriata, Luciano A.
    Dal Peraro, Matteo
    van der Laan, Martin
    Frost, Adam
    Aydin, Halil
    NATURE, 2023, 620 (7976) : 1101 - 1108