Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

被引：0

作者：

Tadato Ban

Takaya Ishihara

Hiroto Kohno

Shotaro Saita

Ayaka Ichimura

Katsumi Maenaka

Toshihiko Oka

Katsuyoshi Mihara

Naotada Ishihara

机构：

[1] Institute of Life Science,Department of Protein Biochemistry

[2] Kurume University,Department of Life Science

[3] Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases,undefined

[4] Laboratory of Biomolecular Science,undefined

[5] Faculty of Pharmaceutical Sciences,undefined

[6] Hokkaido University,undefined

[7] Rikkyo University,undefined

[8] Graduate School of Medical Science,undefined

[9] Kyushu University,undefined

来源：

Nature Cell Biology | 2017年 / 19卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Ban et al. show that optic atrophy 1 (OPA1) and cardiolipin mediate mitochondrial fusion. In contrast, a homotypic trans-OPA1 interaction independent of cardiolipin mediates membrane tethering to form mitochondrial cristae.

引用

页码：856 / 863

页数：7

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