Molecular basis of selective mitochondrial fusion by heterotypic action between OPA1 and cardiolipin

被引：0
|
作者：
Tadato Ban
Takaya Ishihara
Hiroto Kohno
Shotaro Saita
Ayaka Ichimura
Katsumi Maenaka
Toshihiko Oka
Katsuyoshi Mihara
Naotada Ishihara
机构：
[1] Institute of Life Science,Department of Protein Biochemistry
[2] Kurume University,Department of Life Science
[3] Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases,undefined
[4] Laboratory of Biomolecular Science,undefined
[5] Faculty of Pharmaceutical Sciences,undefined
[6] Hokkaido University,undefined
[7] Rikkyo University,undefined
[8] Graduate School of Medical Science,undefined
[9] Kyushu University,undefined
来源：
Nature Cell Biology | 2017年 / 19卷
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摘要：
Ban et al. show that optic atrophy 1 (OPA1) and cardiolipin mediate mitochondrial fusion. In contrast, a homotypic trans-OPA1 interaction independent of cardiolipin mediates membrane tethering to form mitochondrial cristae.
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页码：856 / 863
页数：7
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