Synthesis and properties of pyrazole carbaldehyde bis(2-hydroxyethyl)-dithioacetal hydrochlorides*

被引：0
|
作者：
L. K. Papernaya
A. A. Shatrova
A. I. Albanov
E. V. Rudyakova
G. G. Levkovskaya
机构：
[1] A. E. Favorsky Irkutsk Institute of Chemistry,
[2] Siberian Branch,undefined
[3] Russian Academy of Sciences,undefined
来源：
Chemistry of Heterocyclic Compounds | 2012年 / 47卷
关键词：
bis(2-hydroxyethyl)dithioacetals; 2-mercaptoethanol; 1,3-oxathiolane; pyrazole carbaldehydes; trimethylchlorosilane; acetalization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A simple method has been developed for the synthesis of water-soluble pyrazole derivatives, namely 4-[bis(2-hydroxyethylsulfanyl)methyl]pyrazoles hydrochlorides, by the reaction of a series of pyrazole carbaldehydes with 2-mercaptoethanol in the presence of trimethylchlorosilane. When treated with aqueous ammonia solution the pyrazole-4-carbaldehydes bis(2-hydroxyethyl)dithioacetal hydro-chlorides are converted to the 4-[bis(2-hydroxyethylsulfanyl)methyl]pyrazole free bases.
引用
收藏
页码：1395 / 1404
页数：9
相关论文
共 50 条
  • [41] The effect of synthesis conditions on the properties of poly(2-hydroxyethyl methacrylate) sponges
    Chirila, TV
    Higgins, B
    Dalton, PD
    CELLULAR POLYMERS, 1998, 17 (03) : 141 - 162
  • [42] Synthesis and properties of polyethylene glycol diacrylate/2-hydroxyethyl mathacrylate hydrogels
    Tan Guoxin
    Wang Yingjun
    Guang Yanxia
    HIGH-PERFORMANCE CERAMICS V, PTS 1 AND 2, 2008, 368-372 : 1175 - +
  • [43] Bis[ethyl(2-hydroxyethyl)azanium] 2,2′-disulfanediyldibenzoate
    Broker, Grant A.
    Tiekink, Edward R. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O705 - U5759
  • [44] Synthesis, properties, and crystal and molecular structure of chloro[N,N-bis(2-hydroxyethyl)glycinato]copper(II)
    Yamaguchi, Hiromitsu
    Nagase, Makoto
    Yukawa, Yasuhiko
    Inomata, Yoshie
    Takeuchi, Toshio
    1600, Chemical Society of Japan (61):
  • [45] Modification of the synthesis of N,N′-bis(2-hydroxyethyl)urea and N,N′-bis(2-hydroxypropyl)urea
    Zarzyka-Niemiec, Iwona
    Narog, Dorota
    PRZEMYSL CHEMICZNY, 2008, 87 (10): : 1048 - 1052
  • [46] 5-Amino-1-(2-hydroxyethyl)-1H-pyrazole
    Zhang, Li-Ming
    He, Zhi-Min
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 : O5108 - O5109
  • [47] Terephthalic acid determination from bis(2-hydroxyethyl)terephthalate
    Dumitriu, P
    Butnaru, F
    REVISTA DE CHIMIE, 1997, 48 (01): : 68 - 70
  • [48] BIS(N,N′-BIS(2-HYDROXYETHYL)ETHYLENEDIAMINE)NICKEL(II) SACCHARINATE: SYNTHESIS, CHARACTERIZATION AND CRYSTAL STRUCTURE
    Karadogan, Alparslan
    Karadag, Ahmet
    Yilmaz, Veysel T.
    MACEDONIAN JOURNAL OF CHEMISTRY AND CHEMICAL ENGINEERING, 2015, 34 (01) : 101 - 104
  • [49] Bis[N,N-bis(2-hydroxyethyl)glycinato]cobalt(II)
    Zhao, Jiong-Peng
    Liu, Fu-Chen
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : M848 - U1248
  • [50] PROPERTIES OF POLY(2-HYDROXYETHYL ACRYLATE) NETWORKS
    ANDREOPOULOS, AG
    BIOMATERIALS, 1989, 10 (02) : 101 - 104
12345