Synthesis and properties of pyrazole carbaldehyde bis(2-hydroxyethyl)-dithioacetal hydrochlorides*

被引：0
|
作者：
L. K. Papernaya
A. A. Shatrova
A. I. Albanov
E. V. Rudyakova
G. G. Levkovskaya
机构：
[1] A. E. Favorsky Irkutsk Institute of Chemistry,
[2] Siberian Branch,undefined
[3] Russian Academy of Sciences,undefined
来源：
Chemistry of Heterocyclic Compounds | 2012年 / 47卷
关键词：
bis(2-hydroxyethyl)dithioacetals; 2-mercaptoethanol; 1,3-oxathiolane; pyrazole carbaldehydes; trimethylchlorosilane; acetalization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A simple method has been developed for the synthesis of water-soluble pyrazole derivatives, namely 4-[bis(2-hydroxyethylsulfanyl)methyl]pyrazoles hydrochlorides, by the reaction of a series of pyrazole carbaldehydes with 2-mercaptoethanol in the presence of trimethylchlorosilane. When treated with aqueous ammonia solution the pyrazole-4-carbaldehydes bis(2-hydroxyethyl)dithioacetal hydro-chlorides are converted to the 4-[bis(2-hydroxyethylsulfanyl)methyl]pyrazole free bases.
引用
收藏
页码：1395 / 1404
页数：9
相关论文
共 50 条
  • [31] SYNTHESIS OF SELENIUM CONDENSATION POLYMERS USING BIS(2-HYDROXYETHYL) SELENIDE AND BIS(2-AMINOETHYL) SELENIDE
    KROLL, H
    BOLTON, EF
    JOURNAL OF APPLIED POLYMER SCIENCE, 1970, 14 (09) : 2319 - &
  • [32] Synthesis, structure, and properties of pyrazole-4-carbaldehyde oximes
    O. S. Attaryan
    A. A. Sahakyan
    R. A. Tamazyan
    A. G. Ayvazyan
    G. V. Asratyan
    Russian Journal of General Chemistry, 2012, 82 : 1720 - 1723
  • [33] 1,1-BIS(2-HYDROXYETHYL)HYDRAZONES
    WILEY, RH
    WHITE, HK
    IRICK, G
    JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (02): : 589 - &
  • [34] STRUCTURE OF N,N'-BIS(2-HYDROXYETHYL)PIPERAZINE
    OKAMOTO, K
    FUJII, S
    TOMITA, K
    ARAI, S
    TSUTSUMI, Y
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1992, 48 : 1518 - 1519
  • [35] N,N-BIS(2-HYDROXYETHYL)GLYCINE
    CODY, V
    HAZEL, J
    LANGS, D
    ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1977, 33 (MAR15): : 905 - 907
  • [36] Characterization of Polyurethane Grafted with Bis(2-hydroxyethyl) Terephthalate
    Chung, Yong-Chan
    Kim, Sang Hyeon
    Choi, Jae Won
    Chun, Byoung Chul
    POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING, 2018, 57 (14) : 1474 - 1484
  • [37] UNSATURATED POLYESTERS BASED ON BIS(2-HYDROXYETHYL)TEREPHTHALATE
    TONG, SN
    CHEN, DS
    CHEN, CC
    CHUNG, LZ
    POLYMER, 1983, 24 (04) : 469 - 472
  • [38] In situ synthesis of polyethylene terephthalate nanocomposites using bis (2-hydroxyethyl) phthalate monomer
    Bunekar, Naveen
    Tsai, Tsung-Yen
    Lee, Shu Hui
    Chang, Yu-Lun
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2019, 66 (07) : 698 - 704
  • [39] SYNTHESIS AND PROPERTIES OF POLY(2-HYDROXYETHYL ACRYLATE ETHYLENE DIMETHACRYLATE) GELS
    MATSUMOTO, K
    HIRAYAMA, C
    MOTOZATO, Y
    NIPPON KAGAKU KAISHI, 1983, (07) : 1040 - 1044
  • [40] Synthesis and characterization of poly(butylene terephthalates) modified by hydroquinone bis(2-hydroxyethyl)ether
    Gu, Long
    Lan, Jianwu
    Yang, Qin
    Shi, Kun
    Zheng, Wei
    JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2019, 56 (09): : 871 - 876
12345