Evidence of a role for Th17 cells in the breach of immune tolerance in arthritis

被引：0

作者：

Xinhua Yu

Saleh M Ibrahim

机构：

[1] The Medical College of Xiamen University,Laboratory of Autoimmunity

[2] Xiamen University,Section of Immunoregulation

[3] Research center Borstel,Department of Dermatology

[4] University of Lübeck,undefined

来源：

Arthritis Research & Therapy | / 13卷

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摘要：

Th17 cells are thought to play a pathogenic role in various autoimmune diseases. Cytokines secreted by Th17 cells like IL-17, IL-17F and IL-22 have the capacity to mediate a massive inflammatory response. These proinflammatroy cytokines are likely to mediate the pathogenic potential of Th17 cells. Recent evidence suggests a role for Th17 cells in the breach of immune tolerance. This might shed some new light on the pathogenic role of Th17 cells in autoimmunity.

引用

共 50 条

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