Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration

被引：0
|
作者：
Michael Lattke
Stephanie N. Reichel
Alexander Magnutzki
Alireza Abaei
Volker Rasche
Paul Walther
Dinis P. Calado
Boris Ferger
Thomas Wirth
Bernd Baumann
机构：
[1] Ulm University,Institute of Physiological Chemistry
[2] Ulm University,Core Facility Small Animal MRI
[3] Ulm University,Central Facility for Electron Microscopy
[4] The Francis Crick Institute,Immunity and Cancer Laboratory
[5] Boehringer Ingelheim Pharma GmbH & Co. KG,CNS Diseases Research
[6] The Francis Crick Institute,Neural Stem Cell Biology Laboratory
来源：
Molecular Neurodegeneration | / 12卷
关键词：
NF-kappaB; IKK; Neuroinflammation; Cerebellar ataxia; Purkinje cell degeneration; Bergmann glia; Glutamate transporter; EAAT; Excitotoxicity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Correction: Non-cell-autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse
    Clémentine Vincent
    Javier Gilabert-Juan
    Rachel Gibel-Russo
    Daniel Alvarez-Fischer
    Marie-Odile Krebs
    Gwenaëlle Le Pen
    Alain Prochiantz
    Ariel A. Di Nardo
    Molecular Psychiatry, 2021, 26 : 6481 - 6481
  • [42] Non-cell-autonomous role of myofibroblasts in pulmonary fibrosis through lactate induction of M2 macrophage polarization
    Liu, Gang
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [43] Non-Cell-Autonomous Role Of Myofibroblasts In Pulmonary Fibrosis Through Lactate Induction Of M2 Macrophage Polarization
    Xie, N.
    Ge, J.
    Banerjee, S.
    Cui, H.
    Carter, A. B.
    Liu, R-M
    Antony, V. B.
    Thannickal, V. J.
    Liu, G.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [44] Inhibition of the constitutive activation of NF-κB pathway by an IKK2 inhibitor-AS602868-associates with apoptosis induction in human cutaneous T cell lymphoma
    Sors, A.
    Jean-Louis, F.
    Dubertret, L.
    Parmentier, L.
    Dreano, M.
    Courtois, G.
    Bachelez, H.
    Michel, L.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 : 36 - 36
  • [45] Conditional deletion of activating protein 2α (AP-2α) in the developing retina demonstrates non-cell-autonomous roles for AP-2α in optic cup development
    Bassett, Erin A.
    Pontoriero, Giuseppe F.
    Feng, Weiguo
    Marquardt, Till
    Fini, A. Elizabeth
    Williams, Trevor
    West-Mays, Judith A.
    MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (21) : 7497 - 7510
  • [46] RBL2-E2F-GCN5 guide cell fate decisions during tissue specification by regulating cell-cycle-dependent fluctuations of non-cell-autonomous signaling
    Militi, Stefania
    Nibhani, Reshma
    Jalali, Morteza
    Pauklin, Siim
    CELL REPORTS, 2023, 42 (09):
  • [47] Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism
    Clegg, James M.
    Parkin, Hannah M.
    Mason, John O.
    Pratt, Thomas
    JOURNAL OF NEUROSCIENCE, 2019, 39 (08): : 1386 - 1404
  • [48] MeCP2 deficiency in astrocytes alters synaptogenesis through IL-6 mediated non-cell autonomous mechanism
    Breccia, M.
    Albizzati, E.
    Florio, E.
    Cabasino, C.
    Pozzi, D.
    Boda, E.
    Battaglia, C.
    De Palma, C.
    De Quattro, C.
    Landsberger, N.
    Frasca, A.
    GLIA, 2023, 71 : E567 - E567
  • [49] LMO2 upregulation due to AR deactivation in cancer-associated fibroblasts induces non-cell-autonomous growth of prostate cancer after androgen deprivation
    Chen, Lei
    Wang, Yue-Yang
    Li, Deng
    Wang, Cheng
    Wang, Shi-Yuan
    Shao, Si-Hui
    Zhu, Zheng-Yang
    Zhao, Jing
    Zhang, Yu
    Ruan, Yuan
    Han, Bang-Min
    Xia, Shu-Jie
    Jiang, Chen-Yi
    Zhao, Fu-Jun
    CANCER LETTERS, 2021, 503 : 138 - 150
  • [50] Non-cell-autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse (May, 10.1038/s41380-021-01132-y, 2021)
    Vincent, Clementine
    Gilabert-Juan, Javier
    Gibel-Russo, Rachel
    Alvarez-Fischer, Daniel
    Krebs, Marie-Odile
    Le Pen, Gwenaelle
    Prochiantz, Alain
    Di Nardo, Ariel A.
    MOLECULAR PSYCHIATRY, 2021, 26 (11) : 6481 - 6481
12345