Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration

被引:0
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作者
Michael Lattke
Stephanie N. Reichel
Alexander Magnutzki
Alireza Abaei
Volker Rasche
Paul Walther
Dinis P. Calado
Boris Ferger
Thomas Wirth
Bernd Baumann
机构
[1] Ulm University,Institute of Physiological Chemistry
[2] Ulm University,Core Facility Small Animal MRI
[3] Ulm University,Central Facility for Electron Microscopy
[4] The Francis Crick Institute,Immunity and Cancer Laboratory
[5] Boehringer Ingelheim Pharma GmbH & Co. KG,CNS Diseases Research
[6] The Francis Crick Institute,Neural Stem Cell Biology Laboratory
关键词
NF-kappaB; IKK; Neuroinflammation; Cerebellar ataxia; Purkinje cell degeneration; Bergmann glia; Glutamate transporter; EAAT; Excitotoxicity;
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