Multi-omics on our multitudes

被引：0
|
作者：
Richard A. Voit
Vijay G. Sankaran
机构：
[1] Harvard Medical School,Division of Hematology/Oncology, Boston Children’s Hospital and Department of Pediatric Oncology, Dana
[2] Broad Institute of MIT and Harvard,Farber Cancer Institute
来源：
Nature Genetics | 2022年 / 54卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Clonal expansion of DNMT3A-mutant hematopoietic stem cells is a risk factor for myeloid malignancies and other morbidities. A new study uses multi-modal single-cell genomics to characterize the myeloid differentiation bias of DNMT3A-mutated clones, and finds preferential hypomethylation of binding motifs for key transcriptional regulators.
引用
下载
收藏
页码：1449 / 1450
页数：1
相关论文
共 50 条
  • [21] Multi-omics Pathways Workflow (MOPAW): An Automated Multi-omics Workflow on the Cancer Genomics Cloud
    Nguyen, Trinh
    Bian, Xiaopeng
    Roberson, David
    Khanna, Rakesh
    Chen, Qingrong
    Yan, Chunhua
    Beck, Rowan
    Worman, Zelia
    Meerzaman, Daoud
    CANCER INFORMATICS, 2023, 22
  • [22] Multi-omics Visualization Platform: An extensible Galaxy plug-in for multi-omics data visualization and exploration
    McGowan, Thomas
    Johnson, James E.
    Kumar, Praveen
    Sajulga, Ray
    Mehta, Subina
    Jagtap, Pratik D.
    Griffin, Timothy J.
    GIGASCIENCE, 2020, 9 (04):
  • [23] Immunotherapy and Cancer: The Multi-Omics Perspective
    Donisi, Clelia
    Pretta, Andrea
    Pusceddu, Valeria
    Ziranu, Pina
    Lai, Eleonora
    Puzzoni, Marco
    Mariani, Stefano
    Massa, Elena
    Madeddu, Clelia
    Scartozzi, Mario
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (06)
  • [24] Osteosarcoma Multi-Omics Landscape and Subtypes
    Tang, Shan
    Roberts, Ryan D.
    Cheng, Lijun
    Li, Lang
    CANCERS, 2023, 15 (20)
  • [25] Statistical Challenges in Multi-omics Integration
    Sebastiani, Paola
    Leshchk, Anastasia
    Song, Zeyuan
    Karagiannis, Tanya T.
    Gurinovich, Anastasia
    Bae, Harold
    Li, Mengze
    Monti, Stefano
    GENETIC EPIDEMIOLOGY, 2022, 46 (07) : 530 - 530
  • [26] The multi-omics basis of potato heterosis
    Dawei Li
    Xiaoyue Lu
    Yanhui Zhu
    Jun Pan
    Shaoqun Zhou
    Xinyan Zhang
    Guangtao Zhu
    Yi Shang
    Sanwen Huang
    Chunzhi Zhang
    Journal of Integrative Plant Biology, 2022, (03) : 671 - 687
  • [27] Structural Biology in the Multi-Omics Era
    McCafferty, Caitlyn L.
    Verbeke, Eric J.
    Marcotte, Edward M.
    Taylor, David W.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 60 (05) : 2424 - 2429
  • [28] A Multi-omics View of Single Cells
    Ravindran, Sandeep
    SCIENTIST, 2018, 32 (10): : 56 - 59
  • [29] Mass spectrometry for mitochondrial multi-omics
    Wang, Zengyu
    Liu, Baohong
    Lin, Ling
    Qiao, Liang
    TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2023, 163
  • [30] The multi-omics basis of potato heterosis
    Li, Dawei
    Lu, Xiaoyue
    Zhu, Yanhui
    Pan, Jun
    Zhou, Shaoqun
    Zhang, Xinyan
    Zhu, Guangtao
    Shang, Yi
    Huang, Sanwen
    Zhang, Chunzhi
    JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2022, 64 (03) : 671 - 687
12345