Multi-omics on our multitudes

被引：0
|
作者：
Richard A. Voit
Vijay G. Sankaran
机构：
[1] Harvard Medical School,Division of Hematology/Oncology, Boston Children’s Hospital and Department of Pediatric Oncology, Dana
[2] Broad Institute of MIT and Harvard,Farber Cancer Institute
来源：
Nature Genetics | 2022年 / 54卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Clonal expansion of DNMT3A-mutant hematopoietic stem cells is a risk factor for myeloid malignancies and other morbidities. A new study uses multi-modal single-cell genomics to characterize the myeloid differentiation bias of DNMT3A-mutated clones, and finds preferential hypomethylation of binding motifs for key transcriptional regulators.
引用
收藏
页码：1449 / 1450
页数：1
相关论文
共 50 条
  • [41] Multi-omics shows the (default) way
    Joseph Willson
    Nature Reviews Genetics, 2020, 21 : 134 - 135
  • [42] Visual analysis of multi-omics data
    Swart, Austin
    Caspi, Ron
    Paley, Suzanne
    Karp, Peter D.
    FRONTIERS IN BIOINFORMATICS, 2024, 4
  • [43] Multi-Omics for the Understanding of Brain Diseases
    Villa, Chiara
    Yoon, Jong Hyuk
    LIFE-BASEL, 2021, 11 (11):
  • [44] Integrative Multi-Omics Through Bioinformatics
    Goh, Hoe-Han
    OMICS APPLICATIONS FOR SYSTEMS BIOLOGY, 2018, 1102 : 69 - 80
  • [45] Multi-Omics Approaches in Immunological Research
    Chu, Xiaojing
    Zhang, Bowen
    Koeken, Valerie A. C. M.
    Gupta, Manoj Kumar
    Li, Yang
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [46] The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data
    Paley, Suzanne
    Karp, Peter D.
    METABOLITES, 2024, 14 (01)
  • [47] From 'Omics to Multi-omics Technologies: the Discovery of Novel Causal Mediators
    Mohammadi-Shemirani, Pedrum
    Sood, Tushar
    Pare, Guillaume
    CURRENT ATHEROSCLEROSIS REPORTS, 2023, 25 (02) : 55 - 65
  • [48] Editorial: Artificial intelligence and bioinformatics applications for omics and multi-omics studies
    Facchiano, Angelo
    Heider, Dominik
    Mutarelli, Margherita
    FRONTIERS IN GENETICS, 2024, 15
  • [49] Art-omics: multi-omics meet archaeology and art conservation
    Vilanova, Cristina
    Porcar, Manuel
    MICROBIAL BIOTECHNOLOGY, 2020, 13 (02): : 435 - 441
  • [50] Omics and multi-omics approaches to study the biosynthesis of secondary metabolites in microorganisms
    Palazzotto, Emilia
    Weber, Tilmann
    CURRENT OPINION IN MICROBIOLOGY, 2018, 45 : 109 - 116
12345