Synthesis of 1,2,4-oxadiazolines on soluble polymer support

被引：0
|
作者：
Shang, YJ [1 ]
Shou, WG [1 ]
Wang, YG [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
SYNLETT | 2003年 / 07期
关键词：
poly(ethylene glycol) (PEG); oxadiazolines; imines; cycloaddition; liquid-phase;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general method for the liquid-phase syntheses of 1,2,4-oxadiazolines through a 1,3-dipolar cycloaddition is described. The poly(ethylene glycol) (PEG)-supported imines reacted with nitrile oxides generated in situ from aldoximes, and then the adducts were cleaved from the PEG, to give 1,2,4-oxadiazolines in high yields and excellent purities.
引用
收藏
页码：1064 / 1066
页数：3
相关论文
共 50 条
  • [1] Synthesis of isoxazolyl substituted 1,2,4-oxadiazolines and pyrazolines
    Geng, L
    Lei, M
    Wang, YG
    [J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2005, 25 (06) : 690 - 695
  • [2] Organocatalytic Oxidative Cyclization of Amidoximes for the Synthesis of 1,2,4-Oxadiazolines
    Soni, Vineet Kumar
    Kim, Jun
    Cho, Eun Jin
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2018, 360 (14) : 2626 - 2631
  • [3] MASS SPECTRA OF 1,2,4-OXADIAZOLINES (1)
    SRIVASTAVA, RM
    CLAPP, LB
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1968, 5 (01) : 61 - +
  • [4] SYNTHESIS OF 1,2,4-OXADIAZOLINES HAVING ANTI-FUNGAL ACTIVITY
    RAI, M
    KAUR, B
    [J]. JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1982, 59 (10) : 1197 - 1198
  • [5] REACTION OF OXAZOLES WITH NITROSOBENZENE - A ROUTE TO 1,2,4-OXADIAZOLINES
    SUGA, H
    IBATA, T
    [J]. CHEMISTRY LETTERS, 1991, (07) : 1221 - 1224
  • [6] CLEAVAGE OF N-O BONDS IN 1,2,4-OXADIAZOLINES
    SRIMANNA.G
    SRIVASTA.RM
    CLAPP, LB
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1970, 7 (01) : 151 - &
  • [7] Poly(ethylene glycol) supported liquid-phase synthesis of 1,2,4-oxadiazolines
    Lin, XF
    Zhang, J
    Cui, SL
    Wang, YG
    [J]. SYNTHESIS-STUTTGART, 2003, (10): : 1569 - 1573
  • [8] Rapid one-pot solid-phase synthesis of 1,2,4-oxadiazolines
    Lin, XF
    Cui, SL
    Wang, YG
    [J]. CHEMISTRY LETTERS, 2003, 32 (09) : 842 - 843
  • [9] Synthesis of Novel 3-Aryl-5-dichloromethyl-Δ2-1,2,4-oxadiazolines
    Guirado, Antonio
    Sandoval, Jose A.
    Alarcon, Enrique
    Vera, Maria
    Bautista, Delia
    Galvez, Jesus
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (06) : 1873 - 1878
  • [10] MASS-SPECTRA OF SUBSTITUTED DELTA-2-1,2,4-OXADIAZOLINES .1.
    SRIVASTAVA, RM
    [J]. ORGANIC MASS SPECTROMETRY, 1978, 13 (01): : 14 - 16
12345