Synthesis of 1,2,4-oxadiazolines on soluble polymer support

被引：0
|
作者：
Shang, YJ [1 ]
Shou, WG [1 ]
Wang, YG [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
来源：
SYNLETT | 2003年 / 07期
关键词：
poly(ethylene glycol) (PEG); oxadiazolines; imines; cycloaddition; liquid-phase;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general method for the liquid-phase syntheses of 1,2,4-oxadiazolines through a 1,3-dipolar cycloaddition is described. The poly(ethylene glycol) (PEG)-supported imines reacted with nitrile oxides generated in situ from aldoximes, and then the adducts were cleaved from the PEG, to give 1,2,4-oxadiazolines in high yields and excellent purities.
引用
收藏
页码：1064 / 1066
页数：3
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