Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture

被引：22
|
作者：
Nweke, Mauryn C. [1 ]
Rathore, Anurag S. [2 ]
Bracewell, Daniel G. [1 ]
机构：
[1] UCL, Dept Biochem Engn, Bernard Katz Bldg,Gower St, London WC1E 6BT, England
[2] IIT Delhi, Dept Chem Engn, Delhi 110016, India
来源：
TRENDS IN BIOTECHNOLOGY | 2018年 / 36卷 / 10期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/j.tibtech.2018.01.001
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Poor understanding of the events leading to chromatography column aging makes it difficult to monitor column lifetimes. The lack of established procedures in this area has made it difficult to establish industry standards. Therefore, it is important to understand resin aging mechanisms and techniques to monitor column aging during operation.
引用
下载
收藏
页码：992 / 995
页数：5
相关论文
共 50 条
  • [41] PROBLEMS WITH RESINS IN THE MANUFACTURE OF GRAPHIC PAPERS CONTAINING WOOD
    WEIDENMULLER, J
    NOWAK, E
    PAPIER, 1983, 37 (09): : 437 - 437
  • [42] Flexible, Scalable and Configurable Single-Use Systems for Biopharmaceutical Research and Manufacture
    Szarafinski, Detlev
    CHEMIE INGENIEUR TECHNIK, 2013, 85 (1-2) : 34 - 39
  • [43] INVESTIGATION OF REAL STRUCTURE OF ACICULAR GOETHITE FORMED DURING AGING OF PRECIPITATES IN MANUFACTURE OF CATALYSTS
    KRIVORUCHKO, OP
    BUYANOV, RA
    ABAULINA, LI
    OSTANKOVICH, AA
    DULEPOV, EV
    KOLOMIICHUK, VN
    KINETICS AND CATALYSIS, 1974, 15 (05) : 1168 - 1171
  • [44] HEREDITY, AGING AND LIFETIME OF MAN
    VOITENKO, VP
    TSITOLOGIYA I GENETIKA, 1983, 17 (02): : 65 - 73
  • [45] AGING OF PREDNISONE/MICROCRYSTALLINE CELLULOSE TABLETS, TECHNOLOGICAL AND BIOPHARMACEUTICAL IMPLICATIONS
    MARTINEZPACHECO, R
    VILAJATO, JL
    GUITIANRIVERA, F
    VARELA, J
    PEREZMARCOS, B
    5TH INTERNATIONAL CONFERENCE ON PHARMACEUTICAL TECHNOLOGY, VOLS 1-5, 1989, : C284 - C293
  • [46] The transformation and innovation development of biopharmaceutical industry under the background of aging
    Feng, Jiao
    Zhu, Yan
    Zhang, Jie
    PROCEEDINGS OF THE 2017 2ND INTERNATIONAL CONFERENCE ON FINANCIAL INNOVATION AND ECONOMIC DEVELOPMENT (ICFIED 2017), 2017, 34 : 42 - 45
  • [47] THERMOLUMINESCENCE IN NATURAL RESINS AND THE EFFECT OF AGING
    MARTINEZDEVELASCO, A
    ESPINOSA, G
    GOLZARRI, JI
    CASTANO, VM
    MATERIALS LETTERS, 1992, 15 (03) : 229 - 231
  • [48] Reprint of "Mixed-mode chromatography in pharmaceutical and biopharmaceutical applications"
    Zhang, Kelly
    Liu, Xiaodong
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 130 : 19 - 34
  • [49] CHROMATOGRAPHY OF INSULIN ON ION EXCHANGE RESINS
    SAMSONOV, GV
    FADDEEVA, MD
    BIOCHEMISTRY-MOSCOW, 1956, 21 (03) : 407 - 414
  • [50] Design of Protein A resins for continuous chromatography
    Hicks, Mark
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
12345