Lifetime and Aging of Chromatography Resins during Biopharmaceutical Manufacture

被引：22
|
作者：
Nweke, Mauryn C. [1 ]
Rathore, Anurag S. [2 ]
Bracewell, Daniel G. [1 ]
机构：
[1] UCL, Dept Biochem Engn, Bernard Katz Bldg,Gower St, London WC1E 6BT, England
[2] IIT Delhi, Dept Chem Engn, Delhi 110016, India
来源：
TRENDS IN BIOTECHNOLOGY | 2018年 / 36卷 / 10期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/j.tibtech.2018.01.001
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Poor understanding of the events leading to chromatography column aging makes it difficult to monitor column lifetimes. The lack of established procedures in this area has made it difficult to establish industry standards. Therefore, it is important to understand resin aging mechanisms and techniques to monitor column aging during operation.
引用
下载
收藏
页码：992 / 995
页数：5
相关论文
共 50 条
  • [21] Trends in process development - Rapid process development for biopharmaceutical manufacture
    Byrom, D
    BIOPHARM-THE APPLIED TECHNOLOGIES OF BIOPHARMACEUTICAL DEVELOPMENT, 1999, 12 (07): : 26 - +
  • [22] MANUFACTURE OF BIOPHARMACEUTICAL PROTEINS BY MAMMALIAN-CELL CULTURE SYSTEMS
    TOLBERT, WR
    BIOTECHNOLOGY ADVANCES, 1990, 8 (04) : 729 - 739
  • [23] Medium term planning of biopharmaceutical manufacture using mathematical programming
    Lakhdar, K
    Zhou, YH
    Savery, J
    Titchener-Hooker, NJ
    Papageorgiou, LG
    BIOTECHNOLOGY PROGRESS, 2005, 21 (05) : 1478 - 1489
  • [24] CHEMICAL AND MICROBIAL CHANGES DURING THE MANUFACTURE AND AGING OF BONBEL AND BONBINO CHEESES
    WILLIS, H
    LANGLOIS, BE
    OLEARY, J
    HICKS, CL
    MILCHWISSENSCHAFT-MILK SCIENCE INTERNATIONAL, 1982, 37 (12): : 711 - 715
  • [25] Maximizing the Functional Lifetime of Protein A Resins
    Zhang, Jennifer
    Siva, Sethu
    Caple, Ryan
    Ghose, Sanchayita
    Gronke, Rob
    BIOTECHNOLOGY PROGRESS, 2017, 33 (03) : 708 - 715
  • [26] Maximizing the functional lifetime of Protein A resins
    Zhang, Jennifer
    Ghose, Sanchayita
    Gronke, Robert
    Siva, Sethu
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [27] Maximizing the functional lifetime of Protein A resins
    Zhang, Jennifer
    Caple, Ryan
    Gronke, Rob
    Conley, Lynn
    Cecchini, Doug
    Ghose, Sanchayita
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [28] IMPORTANCE OF THE BASIC REACTIONS IN THE MANUFACTURE OF SYNTHETIC RESINS
    Graur, Iulia P.
    Dragomir, Carmelia Mariana Balanica
    Paduraru, Iulian
    ACTA TECHNICA NAPOCENSIS SERIES-APPLIED MATHEMATICS MECHANICS AND ENGINEERING, 2022, 65 (04): : 1161 - 1168
  • [29] MANUFACTURE OF NON-DRYING ALKYD RESINS
    不详
    PROCESS TECHNOLOGY, 1973, 18 (11): : 423 - 423
  • [30] Streamlined life cycle assessment of single use technologies in biopharmaceutical manufacture
    Budzinski, Kristi
    Constable, David
    D'Aquila, Daniel
    Smith, Phillip
    Madabhushi, Sri R.
    Whiting, Andy
    Costelloe, Tom
    Collins, Michael
    NEW BIOTECHNOLOGY, 2022, 68 : 28 - 36
12345