Biological influence of nanofibrous hydroxyapatite-polycaprolactone membrane on human periodontal ligament cell

被引:0
|
作者
Kim, T. I. [1 ]
Lee, S. J. [1 ]
Ku, Y. [1 ]
Rhyu, I. C. [1 ]
Chung, C. P. [1 ]
Han, S. B. [1 ]
Kim, H. W. [2 ]
机构
[1] Seoul Natl Univ, Dent Res Inst, Seoul, South Korea
[2] Dankook Univ, Inst Tissue Regenerat Engn, Cheonan, South Korea
关键词
hydroxyapatite; membrane; periodontal ligament fibroblast; periodontal tissue regeneration;
D O I
暂无
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Biological effect of the hydroxyapatite-coated nanofibrous membrane was mainly investigated on the proliferation and differentiation of human periodontal ligament fibroblast. SEM revealed favorable cell attachment and spreading appearance on I day and NITS assay showed increased cell proliferation on the hydroxyapatite-coated nanofiber membrane during 14 days. From 7 to 14 days, alkaline phosphatase activity of the hydroxyapatite-coated nanofiber was significantly increased when compared to that of control group. Hydroxyapatite-coated nanofibrous membrane showed prominent mineral formation on day 14. This study revealed that the developed hydroxyapatite-coated nanofibrous membrane had favorable effects on the proliferation and differentiation of human periodontal ligament fibroblast and might be a good candidate material for periodontal tissue regeneration.
引用
收藏
页码:322 / +
页数:2
相关论文
共 50 条
  • [1] Effect of hydroxyapatite-coated nanofibrous membrane on the responses of human periodontal ligament fibroblast
    Park, Sun-Hye
    Kim, Tae-Il
    Ku, Young
    Chung, Chong-Pyoung
    Han, Soo-Boo
    Yu, Ji-Hee
    Lee, Seung-Pyo
    Kim, Hae-Won
    Lee, Hae-Hyoung
    JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 2008, 116 (1349) : 31 - 35
  • [2] Effect of hydroxyapatite-coated nanofibrous membrane on the responses of human periodontal ligament fibroblast (vol 116, pg 31, 2008)
    Park, Sun-Hye
    Kim, Tae-Il
    Ku, Young
    Chung, Chong-Pyoung
    Han, Soo-Boo
    Yu, Ji-Hee
    Lee, Seung-Pyo
    Kim, Hae-Won
    Lee, Hae-Hyoung
    JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 2008, 116 (1351) : 510 - 510
  • [3] Evaluation of Random and Aligned Polycaprolactone Nanofibrous Electrospun Scaffold for Human Periodontal Ligament Engineering in Biohybrid Titanium Implants
    Safi, Ihab N.
    Hussein, Basima Mohammed Ali
    Al-Khafaji, Aseel Mohammed
    Fatalla, Abdalbseet A.
    Al-Shammari, Ahmed M.
    INTERNATIONAL JOURNAL OF DENTISTRY, 2024, 2024
  • [4] Effect of yttrium/hydroxyapatite namocrystals on human periodontal ligament cell behavior.
    Mo, AC
    Wu, HK
    Chen, ZQ
    Zhou, XD
    JOURNAL OF DENTAL RESEARCH, 2003, 82 : 337 - 337
  • [5] Nanofibrous membrane of collagen–polycaprolactone for cell growth and tissue regeneration
    Jae-Jun Lee
    Hye-Sun Yu
    Seok-Jung Hong
    Ishik Jeong
    Jun-Hyeog Jang
    Hae-Won Kim
    Journal of Materials Science: Materials in Medicine, 2009, 20 : 1927 - 1935
  • [6] Influence of polymer content in Ca-deficient hydroxyapatite-polycaprolactone nanocomposites on the formation of microvessel-like structures
    Fuchs, S.
    Jiang, X.
    Gotman, I.
    Makarov, C.
    Schmidt, H.
    Gutmanas, E. Y.
    Kirkpatrick, C. J.
    ACTA BIOMATERIALIA, 2010, 6 (08) : 3169 - 3177
  • [7] Human periodontal ligament cell sheets cultured on amniotic membrane substrate
    Adachi, K.
    Amemiya, T.
    Nakamura, T.
    Honjyo, K.
    Kumamoto, S.
    Yamamoto, T.
    Bentley, A. J.
    Fullwood, N. J.
    Kinoshita, S.
    Kanamura, N.
    ORAL DISEASES, 2014, 20 (06) : 582 - 590
  • [8] Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation
    Xu, Xiongcheng
    Chen, Ziqin
    Xiao, Long
    Xu, Yanmei
    Xiao, Nianqi
    Jin, Weiqiu
    Chen, Yuling
    Li, Yanfen
    Luo, Kai
    JOURNAL OF NANOBIOTECHNOLOGY, 2023, 21 (01)
  • [9] Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation
    Xiongcheng Xu
    Ziqin Chen
    Long Xiao
    Yanmei Xu
    Nianqi Xiao
    Weiqiu Jin
    Yuling Chen
    Yanfen Li
    Kai Luo
    Journal of Nanobiotechnology, 21
  • [10] Treatment of periodontal disease with guided tissue regeneration technique using a hydroxyapatite and polycaprolactone membrane
    Martins, L. M. A.
    Valente, F. L.
    Reis, E. C. C.
    Sepulveda, R. V.
    Perdigao, A. P. L.
    Borges, A. P. B.
    ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA, 2016, 68 (06) : 1413 - 1421