Signal transduction inhibitors, hibarimicins A, B, C, D and G produced by Microbispora -: II.: Structural studies

被引：23

作者：

Hori, H ^{[1
]}

Igarashi, Y

Kajiura, T

Furumai, T

Higashi, K

Ishiyama, T

Uramoto, M

Uehara, Y

Oka, T

机构：

[1] Tamagawa Univ, Fac Agr, Tokyo 1948610, Japan

[2] Toyama Prefectural Univ, Biotechnol Res Ctr, Toyama 9390398, Japan

[3] Natl Inst Infect Dis, Dept Bioact Mol, Shinjuku Ku, Tokyo 1620052, Japan

来源：

JOURNAL OF ANTIBIOTICS | 1998年 / 51卷 / 04期

关键词：

D O I：

10.7164/antibiotics.51.402

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The structure of hibarimicins A, B, C, D and G which are inhibitors for tyrosine specific protein kinase are determined using spectroscopic techniques. Hibarimicins described in this report consist of a common aglycon and six deoxyhexoses. The aglycon contains a highly oxidized naphtylnaphthoquinone as a chromophore. Among them, hibarimicin B was identical with angelmicin B.

引用

页码：402 / 417

页数：16

共 50 条

[21] Tyropeptins A and B, new proteasome inhibitors produced by Kitasatospora sp MK993-dF2 -: II.: Structure determination and synthesis
Momose, I
Sekizawa, R
Hirosawa, S
Ikeda, D
Naganawa, H
Iinuma, H
Takeuchi, T
JOURNAL OF ANTIBIOTICS, 2001, 54 (12): : 1004 - 1012
[22] RAISON DETRE AND STRUCTURAL MODEL FOR THE B-Z TRANSITION OF POLY D(G-C)-STAR-POLY D(G-C)
SAENGER, W
HEINEMANN, U
FEBS LETTERS, 1989, 257 (02) : 223 - 227
[23] STRUCTURAL STUDIES OF THE O-6 MEG.C INTERACTION IN THE D(C-G-C-G-A-A-T-T-C-O6MEG-C-G) DUPLEX
PATEL, DJ
SHAPIRO, L
KOZLOWSKI, SA
GAFFNEY, BL
JONES, RA
BIOCHEMISTRY, 1986, 25 (05) : 1027 - 1036
[24] Erabulenols, inhibitors of cholesteryl ester transfer protein produced by Penicillium sp. FO-5637 -: II.: Structure elucidation of erabulenols A and B
Tabata, N
Tomoda, H
Omura, S
JOURNAL OF ANTIBIOTICS, 1998, 51 (07): : 624 - 628
[25] The number of particles in beta-ray spectra. II. Thorium B and Thorium (C plus D).
Gurney, RW
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-CONTAINING PAPERS OF A MATHEMATICAL AND PHYSICAL CHARACTER, 1926, 112 (761) : 380 - 390
[26] Chemistry of loteprednol etabonate and related steroids. II. Reactions at ring C and NMR structural studies of the resulting compounds
Rachwal, S
Druzgala, P
Liu, ZZ
Vlasak, J
Brewster, ME
Pop, E
STEROIDS, 1998, 63 (04) : 193 - 201
[27] Derivatives of benzo[b]furan. Part II. Structural studies of derivatives of 2-and 3-benzo[b]furancarboxylic acids
Drzewiecka, Aleksandra
Koziol, Anna E.
Pena Ruiz, Tomas
Fernandez Gomez, Manuel
Struga, Marta
Kossakowski, Jerzy
Ostrowska, Kinga
Lis, Tadeusz
STRUCTURAL CHEMISTRY, 2012, 23 (05) : 1617 - 1629
[28] Derivatives of benzo[b]furan. Part II. Structural studies of derivatives of 2- and 3-benzo[b]furancarboxylic acids
Aleksandra Drzewiecka
Anna E. Koziol
Tomas Pena Ruiz
Manuel Fernandez Gomez
Marta Struga
Jerzy Kossakowski
Kinga Ostrowska
Tadeusz Lis
Structural Chemistry, 2012, 23 : 1617 - 1629
[29] TMC-256A1 and C1, new inhibitors of IL-4 signal transduction produced by Aspergillus niger var niger TC 1629
Sakurai, M
Kohno, J
Yamamoto, K
Okuda, T
Nishio, M
Kawano, K
Ohnuki, T
JOURNAL OF ANTIBIOTICS, 2002, 55 (08): : 685 - 692
[30] II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides
Anilkumar, Gopinadhan N.
Selyutin, Oleg
Rosenblum, Stuart B.
Zeng, Qingbei
Jiang, Yueheng
Chan, Tin-Yau
Pu, Haiyan
Wang, Li
Bennett, Frank
Chen, Kevin X.
Lesburg, Charles A.
Duca, Jose
Gavalas, Stephen
Huang, Yuhua
Pinto, Patrick
Sannigrahi, Mousumi
Velazquez, Francisco
Venkatraman, Srikanth
Vibulbhan, Bancha
Agrawal, Sony
Ferrari, Eric
Jiang, Chuan-kui
Huang, H. -C.
Shih, Neng-Yang
Njoroge, F. George
Kozlowski, Joseph A.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (01) : 713 - 717

← 1 2 3 4 5 →