An efficient synthesis of N-protected β-aminoethanesulfonyl chlorides:: Versatile building blocks for the synthesis of oligopeptidosulfonamides

被引：1
|
作者：
Brouwer, AJ [1 ]
Monnee, MCF [1 ]
Liskamp, RMJ [1 ]
机构：
[1] Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Med Chem, NL-3508 TB Utrecht, Netherlands
来源：
SYNTHESIS-STUTTGART | 2000年 / 11期
关键词：
sulfonamides; sulfonyl chloride; amino acid; thioacetate; oxidation;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A very efficient method for the synthesis of beta-amino-ethanesulfonyl chlorides is described. These aliphatic functionalized sulfonyl chlorides are accessible starting from st variety of protected amino acids, including those having functionalized side chains.
引用
收藏
页码：1579 / 1584
页数：6
相关论文
共 50 条
  • [41] Enamide Derivatives: Versatile Building Blocks for Total Synthesis
    Courant, Thibaut
    Dagousset, Guillaume
    Masson, Geraldine
    SYNTHESIS-STUTTGART, 2015, 47 (13): : 1799 - 1826
  • [42] USE OF ETHOXYACETYLENE FOR SYNTHESIS OF N-PROTECTED AMINO-ACIDS
    BANKS, GR
    COHEN, D
    PATTENDE.GE
    THOMAS, JAG
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1967, (02): : 126 - &
  • [43] SYNTHESIS OF ACTIVATED ESTERS OF N-PROTECTED AMINO-ACIDS
    WOLMAN, Y
    LADKANY, D
    FRANKEL, M
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1967, (08): : 689 - &
  • [44] A facile synthesis of N-protected 1-aminoalkylphosphonamidate derivatives
    Xu, JX
    Fu, NY
    SYNTHETIC COMMUNICATIONS, 2000, 30 (22) : 4137 - 4145
  • [45] One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters
    Silveira-Dorta, Gaston
    Alvarez-Mendez, Sergio J.
    Martin, Victor S.
    Padron, Jose M.
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2016, 12 : 957 - 962
  • [46] Efficient solution-phase parallel synthesis of 4-substituted N-protected piperidines
    Wang, XY
    Kauppi, AM
    Olsson, R
    Almqvist, F
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2003, 2003 (23) : 4586 - 4592
  • [47] Diversity-oriented synthesis of enantiopure N-protected β,β-dialkylserines
    Dettwiler, JE
    Lubell, WD
    CANADIAN JOURNAL OF CHEMISTRY, 2004, 82 (02) : 318 - 324
  • [48] Synthesis of N-protected allylic amines from allyl ethers
    Kim, JD
    Lee, MH
    Han, G
    Park, H
    Zee, OP
    Jung, YH
    TETRAHEDRON, 2001, 57 (39) : 8257 - 8266
  • [49] A SIMPLE SYNTHESIS OF N-PROTECTED AMINO-ACID AMIDES
    BOOMGAARDEN, M
    HEINRICH, G
    HENKLEIN, P
    PHARMAZIE, 1992, 47 (09): : 710 - 711
  • [50] Synthesis of functionalized enamines:: A facile and efficient protocol toward N-protected α,β-dehydroamino acid derivatives
    Sun, Yun
    Wang, Xiaozhao
    Zheng, Xiufang
    Zhao, Kang
    SYNLETT, 2008, (06) : 861 - 866
12345