Path2PPI: an R package to predict protein-protein interaction networks for a set of proteins

被引:8
|
作者
Philipp, Oliver [1 ,2 ,3 ]
Osiewacz, Heinz D. [2 ,3 ]
Koch, Ina [1 ,2 ]
机构
[1] Goethe Univ Frankfurt, Fac Comp Sci & Math, Inst Comp Sci, Mol Bioinformat, D-60054 Frankfurt, Germany
[2] Goethe Univ Frankfurt, Cluster Excellence Macromol Complexes, D-60054 Frankfurt, Germany
[3] Goethe Univ Frankfurt, Fac Biosci, Inst Mol Biosci, Mol Dev Biol, D-60054 Frankfurt, Germany
关键词
INTERACTION DATABASE; IREFINDEX;
D O I
10.1093/bioinformatics/btv765
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We introduce PATH2PPI, a new R package to identify protein-protein interaction (PPI) networks for fully sequenced organisms for which nearly none PPI are known. PATH2PPI predicts PPI networks based on sets of proteins from well-established model organisms, providing an intuitive visualization and usability. It can be used to combine and transfer information of a certain pathway or biological process from several reference organisms to one target organism.
引用
收藏
页码:1427 / 1429
页数:3
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