Protein-protein interaction networks: from interactions to networks

被引：0
|
作者：
Cho, SY [1 ]
Park, SG [1 ]
Lee, DH [1 ]
Park, BC [1 ]
机构：
[1] Korea Res Inst Biosci & Biotechnol, Lab Proteome Anal, Taejon 305600, South Korea
来源：
JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY | 2004年 / 37卷 / 01期
关键词：
interaction; mass spectrometry; network; proteomics; yeast two-hybrid;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The goal of interaction proteomics that studies the protein-protein interactions of all expressed proteins is to understand biological processes that are strictly regulated by these interactions. The availability of entire genome sequences of many organisms and high-throughput analysis tools has led scientists to study the entire proteome (Pandey and Mann, 2000). There are various high-throughput methods for detecting protein interactions such as yeast two-hybrid approach and mass spectrometry to produce vast amounts of data that can be utilized to decipher protein functions in complicated biological networks. In this review, we discuss recent developments in analytical methods for large-scale protein interactions and the future direction of interaction proteomics.
引用
收藏
页码：45 / 52
页数：8
相关论文
共 50 条
  • [1] On the structure of protein-protein interaction networks
    Thomas, A
    Cannings, R
    Monk, NAM
    Cannings, C
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2003, 31 : 1491 - 1496
  • [2] Analyzing Protein-Protein Interaction Networks
    Koh, Gavin C. K. W.
    Porras, Pablo
    Aranda, Bruno
    Hermjakob, Henning
    Orchard, Sandra E.
    [J]. JOURNAL OF PROTEOME RESEARCH, 2012, 11 (04) : 2014 - 2031
  • [3] The fragility of protein-protein interaction networks
    Schneider, C. M.
    Andrade, R. F. S.
    Shinbrot, T.
    Herrmann, H. J.
    [J]. EPL, 2011, 95 (01)
  • [4] Querying Protein-Protein Interaction Networks
    Blin, Guillaume
    Sikora, Florian
    Vialette, Stephane
    [J]. BIOINFORMATICS RESEARCH AND APPLICATIONS: 5TH INTERNATIONAL SYMPOSIUM, ISBRA 2009, 2009, 5542 : 52 - 62
  • [5] SnapShot: Protein-Protein Interaction Networks
    Seebacher, Jan
    Gavin, Anne-Claude
    [J]. CELL, 2011, 144 (06) : 1000 - U1
  • [6] Prediction of Protein-Protein Interactions Related to Protein Complexes Based on Protein Interaction Networks
    Liu, Peng
    Yang, Lei
    Shi, Daming
    Tang, Xianglong
    [J]. BIOMED RESEARCH INTERNATIONAL, 2015, 2015
  • [7] Integrating protein-protein interaction networks with phenotypes reveals signs of interactions
    Vinayagam A.
    Zirin J.
    Roesel C.
    Hu Y.
    Yilmazel B.
    Samsonova A.A.
    Neumüller R.A.
    Mohr S.E.
    Perrimon N.
    [J]. Nature Methods, 2014, 11 (1) : 94 - 99
  • [8] Integrating protein-protein interaction networks with phenotypes reveals signs of interactions
    Vinayagam, Arunachalam
    Zirin, Jonathan
    Roesel, Charles
    Hu, Yanhui
    Yilmazel, Bahar
    Samsonova, Anastasia A.
    Neumueller, Ralph A.
    Mohr, Stephanie E.
    Perrimon, Norbert
    [J]. NATURE METHODS, 2014, 11 (01) : 94 - +
  • [9] A Novel Method to Predict Protein-Protein Interactions Based on the Information of Protein-Protein Interaction Networks and Protein Sequence
    Ma, Dai-Chuan
    Diao, Yuan-Bo
    Guo, Yan-Zhi
    Li, Yi-Zhou
    Zhang, Yong-Qing
    Wu, Jiang
    Li, Meng-Long
    [J]. PROTEIN AND PEPTIDE LETTERS, 2011, 18 (09): : 906 - 911
  • [10] Global protein function prediction from protein-protein interaction networks
    Vazquez, A
    Flammini, A
    Maritan, A
    Vespignani, A
    [J]. NATURE BIOTECHNOLOGY, 2003, 21 (06) : 697 - 700
12345