Synthesis of nine-membered, masked enediyne analogues with DNA intercalators and its DNA cleaving activities

被引：25

作者：

Takahashi, T ^{[1
]}

Tanaka, H ^{[1
]}

Yamada, H ^{[1
]}

Matsumoto, T ^{[1
]}

Sugiura, Y ^{[1
]}

机构：

[1] KYOTO UNIV,INST CHEM RES,KYOTO 606,JAPAN

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1997年 / 36卷 / 13-14期

关键词：

DNA cleavage; enediynes; molecular modeling; naphthoic acid;

D O I：

10.1002/anie.199715241

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1524 / 1526

页数：3

共 50 条

[1] DNA cleaving activities of 9-membered masked enediyne analogues possessing DNA intercalator and sugar moieties
Takahashi, T
Tanaka, H
Matsuda, A
Doi, T
Yamada, H
Matsumoto, T
Sasaki, D
Sugiura, Y
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (23) : 3303 - 3306
[2] Recent progress in syntheses of 9-membered masked enediyne analogues and their DNA cleaving activities
Takahashi, T
Tanaka, H
Doi, T
Yamada, H
[J]. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1998, 56 (11) : 987 - 999
[3] DNA cleavage by a nine-membered masked enediyne, an analogue of the kedarcidin and C-1027 chromophores
Takahashi, T
Tanaka, H
Yamada, H
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Sugiura, Y
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (16): : 1835 - 1837
[4] Synthesis of 9-membered masked enediyne analogues possessing DNA intercalator and sugar moieties
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Tanaka, H
Matsuda, A
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[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (23) : 3299 - 3302
[5] DESIGN, SYNTHESIS AND DNA-CLEAVING PROFILES OF HYBRIDS CONTAINING THE NOVEL ENEDIYNE AND NATURALLY-OCCURRING DNA INTERCALATORS
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OHASHI, A
NAKAMURA, T
NAKATA, M
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1993, (19) : 1525 - 1527
[6] CYCLOAROMATIZATION OF A 10-MEMBERED ENEDIYNE DERIVATIVE VIA AN ALLENIC SULFONE INTERMEDIATE AND ITS DNA CLEAVING ACTIVITY
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[J]. TETRAHEDRON LETTERS, 1992, 33 (07) : 957 - 960
[7] Synthesis of 10-membered masked oxaenediyne analogue of kedarcidin-chr and C-1027-chr, and its DNA cleaving activity
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[J]. TETRAHEDRON LETTERS, 1996, 37 (14) : 2433 - 2436
[8] Novel and artificial enediyne DNA cleaving molecules: Molecular design, chemical synthesis, and evaluation
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[J]. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1996, 54 (06) : 503 - 513
[9] SYNTHESIS OF THE DEGRADATION PRODUCT OF AUROMOMYCIN CHROMOPHORE AND DNA-CLEAVING ACTIVITIES OF ITS DERIVATIVES
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[J]. TETRAHEDRON LETTERS, 1986, 27 (12) : 1351 - 1354
[10] SYNTHESIS OF A 9-MEMBERED CYCLIC ANALOG OF THE NEOCARZINOSTATIN CHROMOPHORE AND ITS DNA-CLEAVING ACTIVITY
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TANAKA, H
HIRAI, Y
DOI, T
YAMADA, H
SHIRAKI, T
SUGIURA, Y
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (11): : 1657 - 1659

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