Synthesis of nine-membered, masked enediyne analogues with DNA intercalators and its DNA cleaving activities

被引：25
|
作者：
Takahashi, T [1 ]
Tanaka, H [1 ]
Yamada, H [1 ]
Matsumoto, T [1 ]
Sugiura, Y [1 ]
机构：
[1] KYOTO UNIV,INST CHEM RES,KYOTO 606,JAPAN
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1997年 / 36卷 / 13-14期
关键词：
DNA cleavage; enediynes; molecular modeling; naphthoic acid;
D O I：
10.1002/anie.199715241
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
[No abstract available]
引用
收藏
页码：1524 / 1526
页数：3
相关论文
共 50 条
  • [31] YEAST DNA PRIMASE AND DNA-POLYMERASE ACTIVITIES - AN ANALYSIS OF RNA PRIMING AND ITS COUPLING TO DNA-SYNTHESIS
    SINGH, H
    BROOKE, RG
    PAUSCH, MH
    WILLIAMS, GT
    TRAINOR, C
    DUMAS, LB
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1986, 261 (18) : 8564 - 8569
  • [32] Nucleoside Analogues with a Seven-Membered Sugar Ring: Synthesis and Structural Compatibility in DNA-RNA Hybrids
    Jana, Sunit Kumar
    Harikrishna, S.
    Sudhakar, Sruthi
    El-Khoury, Roberto
    Pradeepkumar, P., I
    Damha, Masad J.
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2022, 87 (05): : 2367 - 2379
  • [33] Synthesis and photo-induced DNA cleaving activities of conjugates of halophenyl derivative and polyamide containing N-methylimidazoles
    Liu, D
    Yuan, G
    Hu, JM
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2006, 82 (03) : 187 - 193
  • [34] Discovery, enantioselective synthesis of myrtucommulone E analogues as tyrosyl-DNA phosphodiesterase 2 inhibitors and their biological activities
    Zhang, Yu
    Yang, Hao
    Wang, Fang-Ting
    Peng, Xing
    Liu, Hai-Yang
    Li, Qing-Jiang
    An, Lin-Kun
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 238
  • [35] Facile synthesis of a dimeric dipyrrole-polyamide and synergetic DNA-cleaving activity of its Cu(II) complex
    Zhou, Chun-Qiong
    Lin, Yan-Ling
    Chen, Jin-Xiang
    Wang, Lu-Sheng
    Yang, Na-Na
    Zeng, Wei
    Chen, Wen-Hua
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (18) : 5853 - 5856
  • [36] Cyclophanes .8. Synthesis and DNA-cleaving activities of novel heterocyclophanes containing two 4,4'-bithiazole rings
    Sasaki, H
    Suehiro, A
    Nakamoto, Y
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1997, 45 (01) : 189 - 193
  • [37] Synthesis, DNA-cleaving activities and cytotoxicities of the copper(II) complexes of pyrrole-polyamide dimers tethered with carboxylate-containing linkers
    Zhou, Chun-Qiong
    Yang, Jian-Wei
    Dong, Cheng
    Lin, Yan-Ling
    Chen, Jin-Xiang
    Chen, Wen-Hua
    [J]. INORGANICA CHIMICA ACTA, 2015, 429 : 168 - 173
  • [38] Synthesis of metal complexes of 2,9-bis(2-hydroxyphenyl)-1,10-phenanthroline and their DNA binding and cleaving activities
    Routier, S
    Joanny, V
    Zaparucha, A
    Vezin, H
    Catteau, JP
    Bernier, JL
    Bailly, C
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1998, (04): : 863 - 868
  • [39] Polyhydric Corrole and Its Gallium Complex: Synthesis, DNA-binding Properties and Photodynamic Activities
    Liang, Zhenhua
    Liu, Haiyang
    Jiang, Guangbin
    Wen, Jinyan
    Liu, Yunjun
    Xiao, Xinyan
    [J]. CHINESE JOURNAL OF CHEMISTRY, 2016, 34 (10) : 997 - 1005
  • [40] SYNTHESIS OF 33-MEMBERED POLYNUCLEOTIDE, CONTAINING THE CORE ATT SITE OF PHAGE-LAMBDA DNA AND ITS CLONING
    KRAVCHENKO, VV
    SERPINSKI, OI
    SINYAKOV, AN
    POPOV, SG
    [J]. BIOORGANICHESKAYA KHIMIYA, 1984, 10 (02): : 220 - 225
12345