Polymorphisms in the Human Apolipoprotein E Receptor 2 Gene in Japanese Sporadic Alzheimer's Disease Patients

被引：3

作者：

Hosoda, Akemi ^{[1
]}

Inoue, Takashi ^{[2
]}

Mao, Chang C. ^{[3
]}

Jeong, Young-Hee ^{[1
]}

Yamagishi, Azumi ^{[1
]}

Ye, Mingjuan ^{[1
]}

Yamamoto, Tokuo ^{[3
]}

Kim, Dong-Ho ^{[1
]}

Saeki, Shigeru ^{[1
]}

机构：

[1] Osaka City Univ, Grad Sch Human Life Sci, Sumiyoshi Ku, Osaka 5588585, Japan

[2] Brain Sci Inst, Lab Dev Neurobiol, Wako, Saitama 3510198, Japan

[3] Tohoku Univ, Inst Dev Aging & Canc, Ctr Adv Genome Res, Aoba Ku, Sendai, Miyagi 9818555, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2010年 / 74卷 / 03期

关键词：

Alzheimer's disease; apoE receptor 2; polymorphisms; DENSITY-LIPOPROTEIN RECEPTOR; VLDL RECEPTOR; ASSOCIATION; EXPRESSION; BINDING; ALLELE; BRAIN;

D O I：

10.1271/bbb.90857

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Apolipoprotein E (apoE) polymorphism is associated with onset of Alzheimer's disease (AD). We found seven polymorphisms in apoE receptor 2 (ApoER2), an apoEbinding receptor, in Japanese sporadic AD patients, but no association of ApoER2 polymorphisms with AD. We consider that the functions of ApoER2 in the brain may be compensated for by those of other apoE-binding receptors such as VLDL receptor.

引用

页码：677 / 679

页数：3

共 50 条

[1] Distribution of apolipoprotein E gene polymorphisms in Japanese patients with Alzheimer's disease and in Japanese centenarians
Yamagata, Z
Asada, T
Kinoshita, A
Zhang, YM
Asaka, A
HUMAN HEREDITY, 1997, 47 (01) : 22 - 26
[2] Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease
Bullido, MJ
Valdivieso, F
MICROSCOPY RESEARCH AND TECHNIQUE, 2000, 50 (04) : 261 - 267
[3] Association between polymorphisms in the apolipoprotein D gene and sporadic Alzheimer's disease
Chen, Yan
Jia, Longfei
Wei, Cuibai
Wang, Fen
Lu, Haiyan
Jia, Jianping
BRAIN RESEARCH, 2008, 1233 : 196 - 202
[4] Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population
Nakamura, S
Toji, H
Maruyama, H
Sasaki, K
Kawakami, H
JOURNAL OF NEUROCHEMISTRY, 1999, 73 : S30 - S30
[5] Apolipoprotein E promoter polymorphism and sporadic Alzheimer's disease in a Japanese population
Toji, H
Maruyama, H
Sasaki, K
Nakamura, S
Kawakami, H
NEUROSCIENCE LETTERS, 1999, 259 (01) : 56 - 58
[6] Association of the estrogen receptor α gene polymorphisms with sporadic Alzheimer's disease
Brandi, ML
Becherini, L
Gennari, L
Racchi, M
Bianchetti, A
Nacmias, B
Sorbi, S
Mecocci, P
Senin, U
Govoni, S
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 265 (02) : 335 - 338
[7] mtDNA polymorphisms in Japanese sporadic Alzheimer's disease
Tanno, Y
Okuizumi, K
Tsuji, S
NEUROBIOLOGY OF AGING, 1998, 19 (01) : S47 - S51
[8] Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease
Seripa, Davide
Panza, Francesco
Franceschi, Marilisa
D'Onofrio, Grazia
Solfrizzi, Vincenzo
Dallapiccola, Bruno
Pilotto, Alberto
AGEING RESEARCH REVIEWS, 2009, 8 (03) : 214 - 236
[9] Low-density lipoprotein receptor-related protein 8 (apolipoprotein E receptor 2) gene polymorphisms in Alzheimer's disease
Ma, SL
Ng, HK
Baum, L
Pang, JCS
Chiu, HFK
Woo, J
Tang, NLS
Lam, LCW
NEUROSCIENCE LETTERS, 2002, 332 (03) : 216 - 218
[10] The effect of promoter polymorphisms of the apolipoprotein E gene and Alzheimer's disease in a Tunisian population
Rassas, A. Achouri
Khiari, H.
Fredj, S. Hadj
Mrabet, A.
Messaoud, T.
EUROPEAN JOURNAL OF NEUROLOGY, 2012, 19 : 744 - 744

← 1 2 3 4 5 →