Solubility of Ibuprofen Sodium Dihydrate in Acetone plus Water Mixtures: Experimental Measurement and Thermodynamic Modeling

被引：14
|
作者：
Dun, Weiqiang [1 ]
Wu, Songgu [1 ]
Tang, Weiwei [1 ]
Wang, Xuemei [1 ]
Sun, Dengqiong [1 ]
Du, Shichao [1 ]
Gong, Junbo [1 ,2 ,3 ]
机构：
[1] Tianjin Univ, State Key Lab Chem Engn, Tianjin 300072, Peoples R China
[2] Tianjin Univ, Coinnovat Ctr Chem & Chem Engn Tianjin, Tianjin 300072, Peoples R China
[3] Tianjin Univ, Tianjin Key Lab Modern Drug Delivery & High Effic, Tianjin 300072, Peoples R China
来源：
JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2014年 / 59卷 / 11期
基金：
中国国家自然科学基金;
关键词：
BINARY SOLVENTS; PURE SOLVENTS; BENZOIC-ACID; HYDROCHLORIDE; SOLVATION;
D O I：
10.1021/je5004093
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
The solubility of ibuprofen sodium dihydrate (ISD) in acetone + water mixtures was measured by the gravimetric method at temperatures ranging from (279.55 to 312.05) K. The measured solubilities were correlated by the modified Apelblat equation, the lambda h (Buchowski) equation, the vant Hoff model, the combined nearly ideal binary solvent/RedlichKister (CNIBS/R-K) equation, and the general single model. The modified Apelblat equation was the best model for correlating the solubility of ISD, while the general single model fits the best for mixed solvents. The standard enthalpy, entropy, and Gibbs energy of the dissociation process of ISD were calculated by the vant Hoff equation and the modified Apelblat model. In addition, there was a maximum value of solubility at a certain acetone mole fraction in the acetone + water mixture.
引用
收藏
页码：3415 / 3421
页数：7
相关论文
共 50 条
  • [41] Solubility Measurement and Thermodynamic Modeling of Benzoic Acid in Monosolvents and Binary Mixtures
    Sandeepa, Kadakanchi
    Kumar, Kosuru Ravi
    Neeharika, Tulasi S. V. R.
    Satyavathi, Bankupalli
    Thella, Prathap Kumar
    JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2018, 63 (06): : 2028 - 2037
  • [42] Ultrasonic studies on sodium thiosulphate and ammonium thiosulphate in water and water plus acetone mixtures
    Dash, UN
    Roy, GS
    Mohanty, S
    INDIAN JOURNAL OF CHEMICAL TECHNOLOGY, 2004, 11 (02) : 178 - 184
  • [43] Solubility and thermodynamic function of apremilast in different (Transcutol plus water) cosolvent mixtures: Measurement, correlation and molecular interactions
    Shakeel, Faiyaz
    Haq, Nazrul
    Alanazi, Fars K.
    Alsarra, Ibrahim A.
    JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2017, 56 : 99 - 107
  • [44] Experimental determination and modeling of methane hydrates in mixtures of acetone and water
    Mainusch, S
    Peters, CJ
    Arons, JD
    Javanmardi, J
    Moshfeghian, M
    JOURNAL OF CHEMICAL AND ENGINEERING DATA, 1997, 42 (05): : 948 - 950
  • [45] Experimental determination and modeling of methane hydrates in mixtures of acetone and water
    Mainusch, S
    Peters, CJ
    deSwaan, AJ
    Javanmardi, J
    NGH '96 - 2ND INTERNATIONAL CONFERENCE ON NATURAL GAS HYDRATES, PROCEEDINGS, 1996, : 71 - 76
  • [46] Budesonide Solubility in 2-Propanol+ Water Mixtures at T = (293.2 to 313.2) K: Experimental Measurement, Thermodynamic Analysis and Mathematical Modeling
    Mohamadian, Esmail
    Zargar, Sanaz Balaye Jame
    Fazlollah, Shokri
    Mostafa, Rostamnezhad
    Sharifnia, Seyed Hesam
    IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION, 2023, 42 (11): : 3870 - 3886
  • [47] Experimental measurement, thermodynamic analysis, and mathematical modeling for budesonide solubility in 1-propanol + water mixtures at T = (293.2 to 313.2) K
    Mohammadian, Esmaeil
    Dashti, Mina
    Martinez, Fleming
    Jouyban, Abolghasem
    BMC CHEMISTRY, 2024, 18 (01)
  • [48] Solubility of Flue Gas or Carbon Dioxide-Nitrogen Gas Mixtures in Water and Aqueous Solutions of Salts: Experimental Measurement and Thermodynamic Modeling
    Hassanpouryouzband, Aliakbar
    Farahani, Mehrdad Vasheghani
    Yang, Jinhai
    Tohidi, Bahman
    Chuvilin, Evgeny
    Istomin, Vladimir
    Bukhanov, Boris
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2019, 58 (08) : 3377 - 3394
  • [49] Experimental Measurement and Thermodynamic Modeling of Hydrate Dissociation Conditions for the Argon plus TBAB plus Water System
    Babaee, Saeedeh
    Hashemi, Hamed
    Mohammadi, Amir H.
    Naidoo, Paramespri
    Ramjugernath, Deresh
    JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2014, 59 (11): : 3900 - 3906
  • [50] Corrigendum of solubility of sodium 2-naphthalenesulfonate in binary (sodium chloride plus water), (sodium sulfate plus water) and (ethanol plus water) solvent mixtures
    Li, Rongrong
    Wang, Xiaoqiang
    Cao, Lijuan
    Zhan, Shiyun
    Zhao, Jia
    Jin, Yanxian
    Chen, Yongfei
    Han, Deman
    JOURNAL OF CHEMICAL THERMODYNAMICS, 2019, 132 : 73 - 75
12345