Development of an end-game strategy towards apoptolidin: a sequential Suzuki coupling approach

被引:32
|
作者
Jin, BH [1 ]
Liu, QS [1 ]
Sulikowski, GA [1 ]
机构
[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
natural product synthesis; trienoate; cross-coupling;
D O I
10.1016/j.tet.2004.10.088
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An end-game strategy towards the synthesis of apoptolidin has been demonstrated in a model study, in which the C( l )-C(15) fragment was successfully assembled using three consecutive Suzuki coupling reactions. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:401 / 408
页数:8
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