Synthesis of N-alkyl-N′-aryl-piperazines via copper-catalyzed C-N bond formation

被引：13
|
作者：
Yavari, Issa [1 ]
Bayat, Mohammad J. [1 ]
Ghazanfarpour-Darjani, Majid [1 ]
机构：
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 41期
关键词：
C-N cross-coupling; DABCO; Copper(I) iodide; N-Alkyl-N '-aryl-piperazines; Aryl halide; Alkyl halide; ONE-POT; MICROWAVE IRRADIATION; AMINATION REACTIONS; SALTS;
D O I：
10.1016/j.tetlet.2014.08.045
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient copper-catalyzed tandem synthesis of N-alkyl-N'-aryl-piperazines from 1,4-diazabicyclo[2.2.2]octane, alkyl halides, and aryl halides in the presence of copper(I) iodide and potassium tert-butoxide in DMSO is described. (C) 2014 Published by Elsevier Ltd.
引用
收藏
页码：5595 / 5596
页数：2
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