Effect of NlpE Overproduction on Multidrug Resistance in Escherichia coli

被引：35
|
作者：
Nishino, Kunihiko [1 ,3 ]
Yamasaki, Seiji [1 ,2 ,4 ]
Hayashi-Nishino, Mitsuko [2 ]
Yamaguchi, Akihito [2 ,4 ]
机构：
[1] Osaka Univ, Lab Microbiol & Infect Dis, Inst Sci & Ind Res, Osaka 5670047, Japan
[2] Osaka Univ, Dept Cell Membrane Biol, Inst Sci & Ind Res, Osaka 5670047, Japan
[3] Japan Sci & Technol Corp, PRESTO, Tokyo 1020075, Japan
[4] Osaka Univ, Sch Pharmaceut Sci, Osaka 5650871, Japan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 05期
基金：
日本科学技术振兴机构; 日本学术振兴会;
关键词：
EXTRACYTOPLASMIC STRESS; OUTER-MEMBRANE; EFFLUX PUMPS; GENES; TRANSPORTERS; SALMONELLA; EXPRESSION; PATHWAY; TYPHIMURIUM; TOLERANCE;
D O I：
10.1128/AAC.01677-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
NlpE, an outer membrane lipoprotein, functions during envelope stress responses in Gram-negative bacteria. In this study, we report that overproduction of NlpE increases multidrug and copper resistance through activation of the genes encoding the AcrD and MdtABC multidrug efflux pumps in Escherichia coli.
引用
收藏
页码：2239 / 2243
页数：5
相关论文
共 50 条
  • [31] IDENTIFICATION OF CUTC AND CUTF(NLPE) GENES INVOLVED IN COPPER TRANSPORT IN ESCHERICHIA-COLI
    GUPTA, SD
    LEE, BTO
    CAMAKARIS, J
    WU, HC
    FASEB JOURNAL, 1995, 9 (06): : A1349 - A1349
  • [32] IDENTIFICATION OF CUTC AND CUTF (NLPE) GENES INVOLVED IN COPPER TOLERANCE IN ESCHERICHIA-COLI
    GUPTA, SD
    LEE, BTO
    CAMAKARIS, J
    WU, HC
    JOURNAL OF BACTERIOLOGY, 1995, 177 (15) : 4207 - 4215
  • [33] Heterologously expressed bacterial and human multidrug resistance proteins confer cadmium resistance to Escherichia coli
    Achard-Joris, M
    van Saparoea, HBV
    Driessen, AJM
    Bourdineaud, JP
    BIOCHEMISTRY, 2005, 44 (15) : 5916 - 5922
  • [34] Multidrug resistance plasmids commonly reprogram the expression of metabolic genes in Escherichia coli
    Hall, Rebecca J.
    Snaith, Ann E.
    Thomas, Matthew J. N.
    Brockhurst, Michael A.
    McNally, Alan
    MSYSTEMS, 2024, 9 (03)
  • [35] Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to β-lactams
    Nishino, K
    Yamada, J
    Hirakawa, H
    Hirata, T
    Yamaguchi, A
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (09) : 3030 - 3033
  • [36] Unexpected complexity of multidrug resistance in the mcr-1-harbouring Escherichia coli
    Rongsui Gao
    Yue Li
    Jingxia Lin
    Chen Tan
    Youjun Feng
    Science China Life Sciences, 2016, 59 : 732 - 734
  • [37] Multidrug resistance following expression of the Escherichia coli marA gene in Mycobacterium smegmatis
    McDermott, PF
    White, DG
    Podglajen, I
    Alekshun, MN
    Levy, SB
    JOURNAL OF BACTERIOLOGY, 1998, 180 (11) : 2995 - 2998
  • [38] Virulence Determinants and Multidrug Resistance of Escherichia coli Isolated from Migratory Birds
    Islam, Md. Saiful
    Nayeem, Md. Mehedi Hasan
    Sobur, Md. Abdus
    Ievy, Samina
    Islam, Md. Amirul
    Rahman, Saifur
    Kafi, Md. Abdul
    Ashour, Hossam M.
    Rahman, Md. Tanvir
    ANTIBIOTICS-BASEL, 2021, 10 (02): : 1 - 13
  • [39] Unexpected complexity of multidrug resistance in the mcr-1-harbouring Escherichia coli
    Rongsui Gao
    Yue Li
    Jingxia Lin
    Chen Tan
    Youjun Feng
    Science China(Life Sciences) , 2016, (07) : 732 - 735
  • [40] Multidrug Resistance Is Common in Escherichia coli Associated with Ileal Crohn's Disease
    Dogan, Belgin
    Scherl, Ellen
    Bosworth, Brian
    Yantiss, Rhonda
    Altier, Craig
    McDonough, Patrick L.
    Jiang, Zhi-Dong
    DuPont, Herbert L.
    Garneau, Philippe
    Harel, Josee
    Rishniw, Mark
    Simpson, Kenneth W.
    INFLAMMATORY BOWEL DISEASES, 2013, 19 (01) : 141 - 150
12345